毒理学数据:
1 。
试验方法：未报告
摄入剂量： 324毫克/千克
测试对象：啮齿动物-兔
毒性类型：急性
毒性作用：详细的毒副作用没有报告以外的其他致死剂量值
2 。
试验方法：皮下
摄入剂量： 798毫克/千克，女性15至19日（县）后受孕
测试对象：啮齿动物-鼠
毒性类型：生殖
毒性作用： 1.胚胎或胎儿死亡
2.中枢神经系统发展异常
3.眼睛/耳朵发展异常
生态学数据:
通常对水是不危害的，若无政府许可，勿将材料排入周围环境。
CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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WY2675000
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CHEMICAL NAME :
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Tellurium dioxide
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CAS REGISTRY NUMBER :
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7446-07-3
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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32
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MOLECULAR FORMULA :
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O2-Te
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MOLECULAR WEIGHT :
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159.60
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WISWESSER LINE NOTATION :
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TE O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>5 gm/kg
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TOXIC EFFECTS :
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Gastrointestinal - hypermotility, diarrhea
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REFERENCE :
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TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands) Volume(issue)/page/year: TNO-96-514
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intratracheal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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80 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - other changes Gastrointestinal - other changes
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REFERENCE :
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AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 39,100,1978
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Unreported
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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324 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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SMSJAR Scottish Medical and Surgical Journal. (Edinburgh, Scotland) For publisher information, see SMDJAK. Volume(issue)/page/year: 26,131,1826 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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50 mg/m3/2H/15W-I
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TOXIC EFFECTS :
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Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle contraction or spasticity Related to Chronic Data - death
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 6(2),44,1962
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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3500 ng/kg/13W-C
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TOXIC EFFECTS :
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Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(10),14,1975 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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798 mg/kg
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SEX/DURATION :
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female 15-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear
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REFERENCE :
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TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 29(2),50A,1984
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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798 mg/kg
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SEX/DURATION :
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female 15-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Specific Developmental Abnormalities - homeostasis
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REFERENCE :
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TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 29(2),50A,1984
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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399 mg/kg
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SEX/DURATION :
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female 15-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
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REFERENCE :
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TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 29(2),50A,1984
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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27930 ug/kg
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SEX/DURATION :
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female 15-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
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REFERENCE :
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TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,66A,1985
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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79800 ug/kg
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SEX/DURATION :
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female 15-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Newborn - stillbirth
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REFERENCE :
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TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,66A,1985 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Te)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.1 mg(Te)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Te)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Te)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Te)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-DENMARK:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-FINLAND:TWA 0.1 mg(Te)/m3;STEL 0.3 mg(Te)/m3 JAN 1993 OEL-FRANCE:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Te)/m3;STEL 0.5 mg(Te)/m3 JAN 1993 OEL-TURKEY:TWA 0.1 mg(Te)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Te)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83727 No. of Facilities: 125 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 502 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83727 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 51 (estimated)
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