19883-41-1

• 常用中文名：D-苯甘氨酸甲酯盐酸盐
• 常用英文名：H-D-Phg-OMe．HCl
• CAS号：19883-41-1
• 分子式：C₉H₁₂ClNO₂
• 分子量：201.650
• 相关类别： 生物化工 氨基酸及其衍生物 甘氨酸类衍生物
• 发布时间：2018-05-07 08:00:00
• 更新时间：2026-07-08 18:41:08
• H-D-Phg-OMe公司。HCl是甘氨酸(HY-Y0966)衍生物[1]。

名称

• 中文名: D-苯甘氨酸甲酯盐酸盐
• 英文名: methyl (2R)-2-amino-2-phenylacetate,hydrochloride
• 中文别名: D-苯甘氨酸甲酯盐酸盐(氯吡格雷杂质); (R)-(-)-2- 苯基甘氨酸甲酯; D苯甘氨酸甲酯盐酸盐/HPLC; 氯化(2-甲氧基-2-氧代-1-苯基-乙基)铵; 氨基(苯基)乙酸盐酸盐甲基; 左旋苯甘氨酸甲酯盐酸盐; 苯甘氨酸甲酯; (R)-(-)-2-苯甘氨酸甲酯 盐酸盐; D-(-)-A-苯甘氨酸甲酯.盐酸盐; 氯化(2-甲氧基-2-氧代-1-苯基乙基)铵; (R)-2-苯基甘氨酸甲酯盐酸盐; D-苯基甘氨酸甲酯盐酸盐; D-苯苷氨酸甲酯盐酸盐; (R)-(-)-2-苯甘氨酸甲酯盐酸盐; (R)-(-)-2-苯甘氨酸甲酯; D-苯甘酸甲酯盐酸盐; 头孢呋辛二聚体1杂质 ( TBFX-DIMER1); (R)-Α-氨基苯乙酸甲酯氢氯化物; 头孢氨苄杂质1(D-苯基甘氨酸甲酯); (R)-Α-氨基苯乙酸甲酯盐酸盐; (R)-(-)-2-苯基甘氨酸甲酯; D-苯甘氨酸甲酯盐酸盐/左旋苯甘氨酸甲酯盐酸盐; D-(-)-2-苯基甘氨酸甲酯盐酸盐; (R)-(-)-2-氨基-2-苯乙酸甲酯盐酸盐; 氯化(2-氧代-2-甲氧基-1-苯基-乙基)铵; 头孢氨苄杂质3盐酸盐; D-(-)-Α-苯甘氨酸甲酯.盐酸盐; 头孢氨苄杂质1盐酸盐; D-苯甘氨酸甲酯; D-苯甘氨酸甲脂盐酸盐; D-A-苯甘氨酸甲酯; 化合物 (R)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE
• 英文别名: Methyl (R)-2-Amino-2-Phenylacetate Hydrochloride; R-Phenyl Glycine methyl ester HCL; Cefalexin Impurity 1 HCl; methyl (2S)-amino(phenyl)ethanoate hydrochloride (1:1); methyl 2-azanyl-2-phenyl-ethanoate; D-(-)-ALPHA-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; D-Phenylglycine methyl·hydrochloride; D(-)-ALPA-PHENYL GLYCINE METHYL ESTER HYDROCHLORIDE; D-Phenylycine methyl ester hydrichloride; D-(-)-2-Phenylglycine Methyl ester hydrochloride; Chalexin Impurity 1 HCl (D-Phenylglycine Methyl Ester HCl); R-phenylglycine methyl ester hydrochloride; H-PH-Phg-Ome hydrochloride; (R)-2-Phenylglycine methyl ester hydrochlorideQ: What is (R)-2-Phenylglycine methyl ester hydrochloride Q: What is the CAS Number of (R)-2-Phenylglycine methyl ester hydrochloride; S)-(+)-2-Phenylglycine methyl ester hydrochloride; (2-methoxy-2-oxo-1-phenylethyl)azanium chloride; H-D-PHG-OME HCL //BP; (2-methoxy-2-oxo-1-phenylethyl)ammonium chloride; (R)-PGME hydrochloride; D-Phenylglycine Methyl Ester Hydrochloride,e.e; L-Phenylglycine methyl ester hydrochloride; (S)-Methyl 2-amino-2-phenylacetate hydrochloride; H-PHG-OME HCL; D-ALPHA-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; D-Phenylglycine methyl ester hydrochloride (HPLC); Benzeneacetic acid, a-amino-, methyl ester, hydrochloride; (S)-a-Amino-benzeneacetic acid methyl ester HCl; (r)-(-)-à-aminophenylacetic acid methyl ester hydrochloride; D-Phg-OMe*HCl; Methyl (2S)-amino(phenyl)acetate hydrochloride (1:1); H-D-Phg-OMe·HCl H-D-Phenylglycine methyl ester hydrochloride; D-phenylglycine methyl ester ·HCl; D-ALPHA-PHENYLGLYCINE METHYLESTER HCL; D-PHENYLGLYCINE-OME HCL; L-Phenylglycine methylester hydrochloride; Methyl (2R)-amino(phenyl)acetate hydrochloride (1:1); (R)-(-)-2-Aminophenylacetic acid methyl ester hydrochloride; (R)-(-)-2-Phenylglycine methyl ester hydrochloride -2-Phenylglycine methyl ester hydrochloride; (R)-(−)-2-Phenylglycine methyl ester hydrochloride; (S)-(+)-2-Phenylglycine methyl ester hydrochloride; MFCD00137487; Chalexin Impurity 1 (D-Phenylglycine Methyl Ester); (S)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; d-(-)-à-phenylglycine methyl ester hydrochloride; D-phenylglycine methyl ester hydrochloride; (R)-(-)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; T0400-4069; Benzeneacetic acid, α-amino-, methyl ester, (αR)-, hydrochloride (1:1); (2-keto-2-methoxy-1-phenyl-ethyl)ammonium chloride; D-ALPHA-Phenylglycine Methylester HCL / H-D-PHG-OME HCL; METHYL (2R)-2-AMINO-2-PHENYLACETATE HYDROCHLORIDE; D-(-)-A-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; (R)-(-)-2-Amino-2-phenylacetic Acid Methyl Ester Hydrochloride; EINECS 243-399-9; (2-methoxy-2-oxo-1-phenyl-ethyl)ammonium chloride; 2-phenylglycine methyl ester hydrochloride; D-Peg-Oe.H Cl; H-D-Phg-OMe hydrochloride; (R)-(-)-2-Phenylglycine Methyl ester hydrochloride >=; D-Phenylycine Methyl Ester Hydrichloride; H-D-PHG-OME HCL; (R)-(-)-alpha-Aminophenylacetic acid Methyl Ester Hydrochloride; methyl amino(phenyl)acetate hydrochloride; (2-methoxy-2-oxo-1-phenyl-ethyl)azanium chloride; Benzeneacetic acid, α-amino-, methyl ester, (αS)-, hydrochloride (1:1); (R)-(-)-2-Phenylglycine methyl ester HCI; H-D-Phg-OMe.HCl; Methyl α-aMinophenylacetate HCl; D-(-)-ɑ-Phenylglycine methyl ester hydrochloride; Chalexin Impurity 1; D-Phenylglycine methyl ester hydrochlorid; methyl (R)-aminophenylacetate hydrochloride; (R)-Methyl 2-amino-2-phenylacetate hydrochloride; D-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE; Chalexin Impurity 1 HCl; H-D-Phg · OCH3 · HCl; D-Phenylglycine Methyl Ester HCl; 2-(2-aminophenyl)acetic acid methyl ester; D-Phenylglycine methyl·hydrochloric acid; methyl (2R)-2-amino-2-phenylacetate hydrochloride; (R)-(-)-2-Phenylglycine Methyl Ester Hydrochloride

物化性质

• 密度: 1.126g/cm3
• 沸点: 238.9ºC at 760mmHg
• 熔点: 189-191 °C(lit.)
• 分子式: C₉H₁₂ClNO₂
• 分子量: 201.650
• 闪点: 104.7ºC
• 精确质量: 201.055649
• PSA: 52.32000
• LogP: 2.36170
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0412mmHg at 25°C
• 储存条件:

  2-8℃

• 稳定性:

  如果按照规则使用和储存则不会分解

  避免接触 氧化物
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:2

  3.氢键受体数量:3

  4.可旋转化学键数量:3

  5.互变异构体数量:无

  6.拓扑分子极性表面积52.3

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:153

  10.同位素原子数量:0

  11.确定原子立构中心数量:1

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

• 更多:

  1.性状：未确定

  2.密度（g/mL,25/4℃）：未确定

  3.相对蒸汽密度（g/mL,空气=1）：未确定

  4.熔点（ºC）：189-191

  5.沸点（ºC,常压）：未确定

  6.沸点（ºC,5.2kPa）：未确定

  7.折射率：未确定

  8.闪点（ºC）：未确定

  9.比旋光度（º）：未确定

  10.自燃点或引燃温度（ºC）：未确定

  11.蒸气压（kPa,25ºC）：未确定

  12.饱和蒸气压（kPa,60ºC）：未确定

  13.燃烧热（KJ/mol）：未确定

  14.临界温度（ºC）：未确定

  15.临界压力（KPa）：未确定

  16.油水（辛醇/水）分配系数的对数值：未确定

  17.爆炸上限（%,V/V）：未确定

  18.爆炸下限（%,V/V）：未确定

  19.溶解性：未确定

生物活性

• 描述: H-D-Phg-OMe公司。HCl是甘氨酸(HY-Y0966)衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

毒性和生态

生态学数据: 对水是稍微危害的，若无政府许可，勿将材料排入周围环境

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H319
• 警示性声明: P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36
• 安全声明 (欧洲): S26-S36/37
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3

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