139264-55-4

• 常用中文名：(S)-4-[(4-硝基苯基)甲基]-2-恶唑烷酮
• 常用英文名：(S)-4-(4-Nitrobenzyl)oxazolidin-2-one
• CAS号：139264-55-4
• 分子式：C₁₀H₁₀N₂O₄
• 分子量：222.197
• 发布时间：2019-02-03 00:40:53
• 更新时间：2026-07-03 17:48:01

名称

• 中文名: (S)-4-(4-硝基苄基)-2-噁唑烷酮
• 英文名: (S)-4-(4-Nitrobenzyl)oxazolidin-2-one
• 中文别名: 佐米曲普坦杂质08; 佐米曲普坦杂质12; 佐米曲坦杂质12; (S)-4-(4-硝基苄基)恶唑烷-2-酮
• 英文别名: 2-Oxazolidinone, 4-[(4-nitrophenyl)methyl]-, (4S); Zomitriptan Impurity 08; (S)-4-(4-Nitrobenzyl)-2(1 H)-oxazolidinone; (4S)-4-(4-Nitrobenzyl)-1,3-oxazolidin-2-one; (S)-4-(4-Nitrobenzyl)-2-oxazolidinone; (S)-4-[(4-Nitrophenyl)methyl]-2-oxazolidinone; Zolmitriptan Impurity 12; 4-[(4-nitrophenyl)methyl]-2-oxazolidinone; R-(+)-4-(4-nitrobenzyl)-2-oxazolidinone; Zolmitriptan Impurity 25

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 509.5±19.0 °C at 760 mmHg
• 分子式: C₁₀H₁₀N₂O₄
• 分子量: 222.197
• 闪点: 261.9±21.5 °C
• 精确质量: 222.064056
• PSA: 84.15000
• LogP: 1.53
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.588

合成路线

75-44-5 89288-22-2 ~76% 139264-55-4

文献：Moloney, Gerard P.; Robertson, Alan D.; Martin, Graeme R.; MacLennan, Steven; Mathews, Neil; Dodsworth, Susan; Sang, Pang Yih; Knight, Cameron; Glen, Robert Journal of Medicinal Chemistry, 1997 , vol. 40, # 15 p. 2347 - 2362

90719-32-7 ~66% 139264-55-4

文献：Ahmed, Sabbir; Adat, Shaheen; Murrells, Annabel; Owen, Caroline P.; Amanuel, Yonas Bioorganic Chemistry, 2002 , vol. 30, # 5 p. 315 - 331

32315-10-9 89288-22-2 ~% 139264-55-4

文献：WO2008/18090 A2, ; Page/Page column 8 ;

949-99-5 ~% 139264-55-4

文献：Journal of Medicinal Chemistry, , vol. 40, # 15 p. 2347 - 2362

17193-40-7 ~% 139264-55-4

文献：Journal of Medicinal Chemistry, , vol. 40, # 15 p. 2347 - 2362

63-91-2 ~% 139264-55-4

文献：Journal of Medicinal Chemistry, , vol. 40, # 15 p. 2347 - 2362

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