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14729-29-4

14729-29-4结构式

常用中文名：roridin a
常用英文名：roridin a
CAS号：14729-29-4
分子式：C₂₉H₄₀O₉
分子量：532.62200
发布时间：2017-03-12 07:42:27
更新时间：2024-01-09 00:00:42
Roridin A是拟南芥花粉发育的抑制剂。Roridin A是从真菌Cylindrocarpon sp.中分离出来的。Roridin A在浓度为2μM时抑制花粉发育[1]。

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中文名	7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A
英文名	roridin a
英文别名	roridin A from myrothecium sp cryst roridana Roridin A,Roridin C roridinea Einecs 238-783-8 roridin a from myrothecium sp. MFCD00055569 7'-Deoxo-7'-[(1R)-1-Hydroxyethyl]-(7'R)-Verrucarin A

描述	Roridin A是拟南芥花粉发育的抑制剂。Roridin A是从真菌Cylindrocarpon sp.中分离出来的。Roridin A在浓度为2μM时抑制花粉发育[1]。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. AtsumiShimada, et al. Roridin A and verrucarin A, inhibitors of pollen development in Arabidopsis thaliana, produced by Cylindrocarpon sp.

密度	1.29g/cm3
沸点	752.4ºC at 760 mmHg
分子式	C₂₉H₄₀O₉
分子量	532.62200
闪点	246ºC
精确质量	532.26700
PSA	124.05000
LogP	2.39340
外观性状	粉末
蒸汽压	3.92E-26mmHg at 25°C
折射率	1.58

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VL0355000

CHEMICAL NAME :: Roridin A

CAS REGISTRY NUMBER :: 14729-29-4

LAST UPDATED :: 198708

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C29-H40-O9

MOLECULAR WEIGHT :: 532.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIBIAU Biotechnology and Bioengineering. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.4- 1962- Volume(issue)/page/year: 10,445,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2300 ug/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from large intestine Gastrointestinal - hypermotility, diarrhea

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985

危害码 (欧洲)	T+: Very toxic;
风险声明 (欧洲)	R28
安全声明 (欧洲)	28-36/37-45
危险品运输编码	UN 3462 6.1/PG 1
危险类别	6.1(a)

76685-82-0结构式

76685-82-0

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3148-09-2结构式

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16891-85-3结构式

16891-85-3

14729-29-4结构式

14729-29-4

详细

文献：Jarvis, Bruce B.; Pavanasasivam, Gowsala; Holmlund, C. E.; DeSilva, Tuley; Stahly, G. Patrick; Mazzola, Eugene P. Journal of the American Chemical Society, 1981 , vol. 103, # 2 p. 472 - 474

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