DC Chemicals Limited
China
Product Name: Roridin A
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Purity: 98.0%
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Contact: Tony Cao

14729-29-4

14729-29-4 structure

14729-29-4 structure

Name: roridin a
Chemical Name: roridin a
CAS Number: 14729-29-4
Molecular Formula: C₂₉H₄₀O₉
Molecular Weight: 532.62200
Create Date: 2017-03-12 07:42:27
Modify Date: 2024-01-09 00:00:42
Roridin A is an inhibitor of pollen development in Arabidopsis thaliana. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A inhibits the pollen development at concentrations of 2 μM[1].

Name	roridin a
Synonyms	roridin A from myrothecium sp cryst roridana Roridin A,Roridin C roridinea Einecs 238-783-8 roridin a from myrothecium sp. MFCD00055569 7'-Deoxo-7'-[(1R)-1-Hydroxyethyl]-(7'R)-Verrucarin A

Description	Roridin A is an inhibitor of pollen development in Arabidopsis thaliana. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A inhibits the pollen development at concentrations of 2 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. AtsumiShimada, et al. Roridin A and verrucarin A, inhibitors of pollen development in Arabidopsis thaliana, produced by Cylindrocarpon sp.

Density	1.29g/cm3
Boiling Point	752.4ºC at 760 mmHg
Molecular Formula	C₂₉H₄₀O₉
Molecular Weight	532.62200
Flash Point	246ºC
Exact Mass	532.26700
PSA	124.05000
LogP	2.39340
Vapour Pressure	3.92E-26mmHg at 25°C
Index of Refraction	1.58

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VL0355000

CHEMICAL NAME :: Roridin A

CAS REGISTRY NUMBER :: 14729-29-4

LAST UPDATED :: 198708

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C29-H40-O9

MOLECULAR WEIGHT :: 532.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIBIAU Biotechnology and Bioengineering. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.4- 1962- Volume(issue)/page/year: 10,445,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2300 ug/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from large intestine Gastrointestinal - hypermotility, diarrhea

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985

Hazard Codes	T+: Very toxic;
Risk Phrases	R28
Safety Phrases	28-36/37-45
RIDADR	UN 3462 6.1/PG 1
Hazard Class	6.1(a)

76685-82-0 structure

76685-82-0

~%

3148-09-2 structure

3148-09-2

16891-85-3 structure

16891-85-3

14729-29-4 structure

14729-29-4

Detail

Literature: Jarvis, Bruce B.; Pavanasasivam, Gowsala; Holmlund, C. E.; DeSilva, Tuley; Stahly, G. Patrick; Mazzola, Eugene P. Journal of the American Chemical Society, 1981 , vol. 103, # 2 p. 472 - 474

Precursor 1
76685-82-0
DownStream 4
74516-67-9 87532-31-8 87532-28-3 87583-91-3