537-05-3

• 常用中文名：茴胍卡因
• 常用英文名：Guanicaine
• CAS号：537-05-3
• 分子式：C₂₃H₂₆ClN₃O₃
• 分子量：427.92400
• 发布时间：2018-08-05 19:23:24
• 更新时间：2024-01-31 12:01:22

名称

• 中文名: 茴胍卡因
• 英文名: 2-(4-ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine,hydrochloride
• 英文别名: Guanicaine; Acoin; Diparaanisyl-monophenethyl-guanidin-hydrochlorid [German]; 2-(4-Ethoxyphenyl)-1,3-bis(4-methoxyphenyl)guanidine hydrochloride; Dianisyl-monophenethylguanidine hydrochloride; Akoin hydrochlorid [German]; Phenodianisyl; Phenodianisyl hydrochloride; Acoine; Acoin hydrochloride

物化性质

• 沸点: 545.9ºC at 760mmHg
• 分子式: C₂₃H₂₆ClN₃O₃
• 分子量: 427.92400
• 闪点: 284ºC
• 精确质量: 427.16600
• PSA: 64.11000
• LogP: 6.26220

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MF2000000 CHEMICAL NAME : Guanidine, 2-(p-ethoxyphenyl)-1,3-bis(p-methoxyphenyl)-, hydrochloride CAS REGISTRY NUMBER : 537-05-3 LAST UPDATED : 199012 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C23-H25-N3-O3.Cl-H MOLECULAR WEIGHT : 427.97 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Behavioral - excitement REFERENCE : HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 Volume(issue)/page/year: -,-,1933 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 53 mg/kg TOXIC EFFECTS : Behavioral - general anesthetic REFERENCE : WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1291,1935 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MEIEDD Merck Index. (Merck & Co., Inc., Rahway, NJ 07065) 10th ed. 1983. For publisher information, see 85KYAH. Volume(issue)/page/year: 10,1043,1983 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1291,1935

安全

• 海关编码: 2925290090

海关

海关编码	2925290090
中文概述	2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%