121250-06-4

• 常用中文名：14-氯柔红霉素
• 常用英文名：14-Chloro Daunorubicin
• CAS号：121250-06-4
• 分子式：C₂₇H₂₈ClNO₁₀
• 分子量：561.96500
• 发布时间：2017-12-18 19:39:45
• 更新时间：2024-01-17 17:36:18

名称

• 中文名: 14-氯柔红霉素
• 英文名: 14-Chloro Daunorubicin
• 英文别名: 14-chlorodaunorubicin; 14-ChlororuboMycin; 10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-(2-chloroacetyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione; 14-ChlorodaunoMycin

物化性质

• 密度: 1.6g/cm3
• 沸点: 793.8ºC at 760mmHg
• 分子式: C₂₇H₂₈ClNO₁₀
• 分子量: 561.96500
• 闪点: 433.9ºC
• 精确质量: 561.14000
• PSA: 185.84000
• LogP: 1.94810
• 蒸汽压: 1.43E-26mmHg at 25°C
• 折射率: 1.695

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QI9325500 CHEMICAL NAME : 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha -L-lyxo- hexopyranosyl)oxy)-8-(chloroacetyl)-1-methoxy-6,8,11- trihydroxy-, (8S-cis)- CAS REGISTRY NUMBER : 121250-06-4 LAST UPDATED : 199206 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C27-H28-Cl-N-O10 MOLECULAR WEIGHT : 562.01 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 33500 ug/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : ANKHEW Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. (V/O Me zhdunarodnaya Kniga, 113095 Moskow, USSR) V.33- 1988- Volume(issue)/page/year: 35(2),24,1990