5373-87-5

• 常用中文名：N-羟基-4-甲氧基苯羧酰亚胺
• 常用英文名：N-HYDROXY-4-METHOXY-BENZAMIDINE
• CAS号：5373-87-5
• 分子式：C₈H₁₀N₂O₂
• 分子量：166.17700
• 发布时间：2018-09-22 22:33:20
• 更新时间：2024-01-08 22:49:32
• 下载msds

名称

• 中文名: 4-甲氧基苄胺肟
• 英文名: N'-Hydroxy-4-methoxybenzenecarboximidamide,
• 中文别名: N-羟基-4-甲氧基苯羧酰亚胺
• 英文别名: 4-Methoxybenzamide oxime; N-HYDROXY-4-METHOXY-BENZAMIDINE; N'-HYDROXY-4-METHOXYBENZENECARBOXIMIDAMIDE; p-anisamidoxime; anisamidoxime; 4-Methoxybenzamidoxime; 4-methoxyphenylcarboxamidoxime; N'-Hydroxy-4-methoxybenzenecarboximideamide; p-methoxybenzamide oxime; 4-Methoxybenzenecarboxamide oxime; n-hydroxy-4-methoxy-benzenecarboximidamid; N-hydroxy-4-methoxybenzimidamide; 4-methoxybenzamidoxime

物化性质

• 密度: 1.21g/cm3
• 沸点: 344.8 °C at 760 mmHg
• 熔点: 122-128℃
• 分子式: C₈H₁₀N₂O₂
• 分子量: 166.17700
• 精确质量: 166.07400
• PSA: 67.84000
• LogP: 1.49000
• 储存条件: 2-8°C

MSDS

Name: N -Hydroxy-4-methoxybenzenecarboximidamide Material Safety Data Sheet Synonym: CAS: 5373-87-5 Section 1 - Chemical Product MSDS Name:N -Hydroxy-4-methoxybenzenecarboximidamide Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 5373-87-5 Vinyl Sulfone polystyrene resin 95+% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 44 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Risk of explosion if heated under confinement. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Violently decomposes when heated under confinement. Risk of explosion if heated under confinement. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 5373-87-5: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Off white Odor: Without to slight pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 122 - 128 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H10N2O2 Molecular Weight: 166.18 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases, peroxides. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 5373-87-5: BZ3425000 LD50/LC50: Not available. Carcinogenicity: Vinyl Sulfone polystyrene resin - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. R 44 Risk of explosion if heated under confinement. Safety Phrases: S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 5373-87-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 5373-87-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 5373-87-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BZ3425000 CHEMICAL NAME : p-Anisamidoxime CAS REGISTRY NUMBER : 5373-87-5 LAST UPDATED : 199206 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H10-N2-O2 MOLECULAR WEIGHT : 166.20 WISWESSER LINE NOTATION : QNUYZR DO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01974

安全

• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2925290090

合成路线

874-90-8 ~88% 5373-87-5

文献：Kharchenko; Detistov; Orlov Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 600 - 605 Khim. Geterotsikl. Soedin., 2008 , # 5 p. 758 - 764,7

3717-22-4 ~% 5373-87-5

文献：Miller Chemische Berichte, 1889 , vol. 22, p. 2794

3717-21-3 ~% 5373-87-5

文献：Kinney et al. Journal of the American Chemical Society, 1933 , vol. 55, p. 3418,3421

38435-51-7 ~% 5373-87-5

文献：Kinney et al. Journal of the American Chemical Society, 1933 , vol. 55, p. 3418,3421

860584-94-7 ~% 5373-87-5

文献：Kinney et al. Journal of the American Chemical Society, 1933 , vol. 55, p. 3418,3421

874-90-8 ~% 3424-93-9 5373-87-5

文献：Kovacs, Dora; Woelfling, Janos; Szabo, Nikoletta; Szecsi, Mihaly; Kovacs, Ida; Zupko, Istvan; Frank, Eva European Journal of Medicinal Chemistry, 2013 , vol. 70, p. 649 - 660

64-17-5 7803-49-8 874-90-8 ~% 5373-87-5

文献：Miller Chemische Berichte, 1889 , vol. 22, p. 2794

上下游产品

上游产品  7
874-90-8 3717-22-4 3717-21-3 38435-51-7
860584-94-7 64-17-5 7803-49-8
下游产品  7
94192-18-4 55667-07-7 1023375-50-9 2387-23-7
3424-93-9 874-90-8 57238-76-3

海关

海关编码	2925290090
中文概述	2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%