中文名 | 盐酸多虑平 |
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英文名 | Doxepin Hydrochloride |
中文别名 |
盐酸多塞平
盐酸多塞平 多塞平盐酸盐 11-(3-二甲基氨基亚丙基)-6,11-二氢二苯并[b,e]氧杂卓盐酸盐 N,N-二甲基-3-二苯并[B,E]-庚英-11(6H)亚基-丙胺盐酸盐 盐酸多噻平 |
英文别名 |
P 3693A
Curatin 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1) 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride (1:1) 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine hydrochloride (1:1) Doxepin hydrochloride EINECS 214-966-8 Adapin N,N-Dimethyldibenz[b,e]oxepin-D11(6H),g-propylamine Hydrochloride 3-Dibenzo[b,e]oxepin-11(6H)-yliden-N,N-dimethylpropan-1-aminhydrochlorid Quitaxon MFCD00079135 1-propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride doxepin HCl Novoxapin [Ester] 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepine Hydrochloride MF 10 HCl 3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride N,N-Dimethyldibenz[b,e]oxepin-δ11(6H),γ-propylamine hydrochloride Novoxapin 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride Doxepin (Hydrochloride) |
描述 | Doxepin盐酸盐能抑制5-羟色胺和去甲肾上腺素的重吸收,有抗抑郁活性。 |
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相关类别 | |
参考文献 |
沸点 | 413.3ºC at 760mmHg |
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熔点 | 187-189°C |
分子式 | C19H22ClNO |
分子量 | 315.837 |
闪点 | 121.3ºC |
精确质量 | 315.138977 |
PSA | 12.47000 |
LogP | 4.76440 |
外观性状 | 白色至灰白色粉末 |
蒸汽压 | 4.87E-07mmHg at 25°C |
储存条件 | 库房通风低温干燥,与食品原料分开存放 |
稳定性 | Store in Freezer at -20°C |
水溶解性 | 1 M HCl: 50 mg/mL |
Material Safety Data Sheet
Section1. Identification of the substance Product Name: Doxepin HCl Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H301:Toxic if swallowed
H361:Suspected of damaging fertility or the unborn child P281:Use personal protective equipment as required P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P308+P313:IF exposed or concerned: Get medical advice/attention P321:Specific treatment (see on this label) P405:Store locked up Section3. Composition/information on ingredients. Ingredient name:Doxepin HCl CAS number:1229-29-4 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified No data Boiling point: Melting point:No data Flash point:No data Density:No data Molecular formula: C19H21NO.ClH Molecular weight: 315.8 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information UN Number:UN2811Class: 6.1Packing group: III Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. (Doxepin HCl) Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
符号 |
GHS02, GHS06, GHS08 |
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信号词 | Danger |
危害声明 | H225-H301 + H311 + H331-H370 |
警示性声明 | P210-P260-P280-P301 + P310-P311 |
个人防护装备 | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
危害码 (欧洲) | T,F |
风险声明 (欧洲) | R25 |
安全声明 (欧洲) | 36/37/39-45 |
危险品运输编码 | UN 2811 6.1/PG 3 |
WGK德国 | 3 |
RTECS号 | HQ4375000 |
包装等级 | III |
危险类别 | 6.1(b) |
海关编码 | 2932999099 |
~% 1229-29-4 |
文献:Synthetic Communications, , vol. 19, # 19 p. 3349 - 3352 |
~% 1229-29-4 |
文献:Synthetic Communications, , vol. 19, # 19 p. 3349 - 3352 |
~% 1229-29-4 |
文献:Synthetic Communications, , vol. 19, # 19 p. 3349 - 3352 |
~% 1229-29-4 |
文献:Synthetic Communications, , vol. 19, # 19 p. 3349 - 3352 |
~% 1229-29-4 |
文献:Synthetic Communications, , vol. 11, # 3 p. 241 - 246 |
上游产品 6 | |
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下游产品 6 | |
海关编码 | 2932999099 |
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中文概述 | 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |