133261-10-6

• 常用中文名：3-(叔丁基)-1-甲基-1H-吡唑-5-羧酸乙酯
• 常用英文名：Ethyl 3-(Tert-Butyl)-1-Methyl-1h-Pyrazole-5-Carboxylate
• CAS号：133261-10-6
• 分子式：C₁₁H₁₈N₂O₂
• 分子量：210.27300
• 发布时间：2018-12-21 11:13:38
• 更新时间：2024-01-09 10:24:34

名称

• 中文名: 3-(叔丁基)-1-甲基-1H-吡唑-5-羧酸乙酯
• 英文名: ethyl 5-tert-butyl-2-methylpyrazole-3-carboxylate
• 中文别名: 1-甲基-3-叔丁基吡唑-5-甲酸乙酯
• 英文别名: 3-(1,1-dimethylethyl)-1-methyl-1H-pyrazole-5-carboxylic acid ethyl ester; 1H-Pyrazole-5-carboxylicacid,3-(1,1-dimethylethyl)-1-methyl-,ethyl ester; ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate; 5-tert-butyl-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester; Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate; Ethyl 3-tert-Butyl-1-methylpyrazole-5-carboxylate

物化性质

• 密度: 1.04g/cm3
• 沸点: 299.2ºC at 760 mmHg
• 分子式: C₁₁H₁₈N₂O₂
• 分子量: 210.27300
• 闪点: 134.8ºC
• 精确质量: 210.13700
• PSA: 44.12000
• LogP: 1.89430
• 蒸汽压: 0.00121mmHg at 25°C
• 折射率: 1.502
• 储存条件: 室温，干燥

MSDS

Name: Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate tech Material Safety Data Sheet Synonym: CAS: 133261-10-6 Section 1 - Chemical Product MSDS Name:Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate tech Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 133261-10-6 Ethyl 3-(tert-butyl)-1-methyl-1H-pyraz unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 133261-10-6: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 116 deg C @15mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H18N2O2 Molecular Weight: 210 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases, amines. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 133261-10-6 unlisted. LD50/LC50: Not available. Carcinogenicity: Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 133261-10-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 133261-10-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 133261-10-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 安全声明 (欧洲): S24/25
• 海关编码: 2933199090

合成路线

77-78-1 83405-70-3 ~74% 133261-10-6

文献：Galapagos NV Patent: WO2009/71706 A1, 2009 ; Location in patent: Page/Page column 43-44 ; WO 2009/071706 A1

13395-36-3 60-34-4 ~% 133261-10-6

文献：US2011/218197 A1, ; Page/Page column 44 ; US 20110218197 A1

13395-36-3 60-34-4 ~71% 133261-10-6 194289-30-0

文献：Journal of Organic Chemistry, , vol. 62, # 17 p. 5908 - 5919

75-97-8 ~% 133261-10-6

文献：Journal of Organic Chemistry, , vol. 62, # 17 p. 5908 - 5919

上下游产品

上游产品  5
77-78-1 83405-70-3 13395-36-3 60-34-4
75-97-8
下游产品  2
160842-62-6 175277-11-9

海关

海关编码	2933199090
中文概述	2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%