Name | ethyl 5-tert-butyl-2-methylpyrazole-3-carboxylate |
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Synonyms |
3-(1,1-dimethylethyl)-1-methyl-1H-pyrazole-5-carboxylic acid ethyl ester
1H-Pyrazole-5-carboxylicacid,3-(1,1-dimethylethyl)-1-methyl-,ethyl ester ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate 5-tert-butyl-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate Ethyl 3-tert-Butyl-1-methylpyrazole-5-carboxylate |
Density | 1.04g/cm3 |
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Boiling Point | 299.2ºC at 760 mmHg |
Molecular Formula | C11H18N2O2 |
Molecular Weight | 210.27300 |
Flash Point | 134.8ºC |
Exact Mass | 210.13700 |
PSA | 44.12000 |
LogP | 1.89430 |
Vapour Pressure | 0.00121mmHg at 25°C |
Index of Refraction | 1.502 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 133261-10-6: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 116 deg C @15mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H18N2O2 Molecular Weight: 210 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases, amines. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 133261-10-6 unlisted. LD50/LC50: Not available. Carcinogenicity: Ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 133261-10-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 133261-10-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 133261-10-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
Safety Phrases | S24/25 |
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HS Code | 2933199090 |
~74% 133261-10-6 |
Literature: Galapagos NV Patent: WO2009/71706 A1, 2009 ; Location in patent: Page/Page column 43-44 ; WO 2009/071706 A1 |
~% 133261-10-6 |
Literature: US2011/218197 A1, ; Page/Page column 44 ; US 20110218197 A1 |
~71% 133261-10-6 |
Literature: Journal of Organic Chemistry, , vol. 62, # 17 p. 5908 - 5919 |
~% 133261-10-6 |
Literature: Journal of Organic Chemistry, , vol. 62, # 17 p. 5908 - 5919 |
Precursor 5 | |
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DownStream 2 | |
HS Code | 2933199090 |
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Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |