460-39-9

• 常用中文名：3,3,3-三氟丙胺
• 常用英文名：3,3,3-Trifluoro-1-propanamine
• CAS号：460-39-9
• 分子式：C₃H₆F₃N
• 分子量：113.082
• 发布时间：2018-06-28 21:56:46
• 更新时间：2024-01-06 18:57:27
• 3,3,3-三氟丙胺的转氨酶可以被分为5类：天冬氨酸转氨酶、芳香族转氨酶、ω-转氨酶、支链转氨酶和D-转氨酶。由于ω-转氨酶可以催化一些特定的底物,因此具有更好的工业应用价值。

名称

• 中文名: 3,3,3-三氟丙胺
• 英文名: 3,3,3-trifluoropropan-1-amine
• 英文别名: 3,3,3-trifluoropropan-1-amine; 3,3,3-trifluoropropyl-1-amine; Trifluoropropylamine; 1-Propanamine, 3,3,3-trifluoro-; 1-amino-3,3,3-trifluoropropane; 3,3,3-trifluoro-n-propylamine; 3,3,3-Trifluoro-1-propanamine; CF3CH2CH2NH2; 3,3,3-Trifluoropropylamine; PROPYLAMINE,3,3,3-TRIFLUORO

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 30.6±40.0 °C at 760 mmHg
• 分子式: C₃H₆F₃N
• 分子量: 113.082
• 闪点: -20.2±12.0 °C
• 精确质量: 113.045235
• PSA: 26.02000
• LogP: 0.52
• 蒸汽压: 615.8±0.1 mmHg at 25°C
• 折射率: 1.329
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UI5201000 CHEMICAL NAME : Propylamine, 3,3,3-trifluoro- CAS REGISTRY NUMBER : 460-39-9 BEILSTEIN REFERENCE NO. : 1734764 LAST UPDATED : 199709 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C3-H6-F3-N HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 29 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,116,1982 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 600 mg/m3 TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 14(11),59,1970

安全

• 危害码 (欧洲): C: Corrosive;
• 安全声明 (欧洲): 26-39
• 海关编码: 2921199090

合成路线

460-75-3 ~% 460-39-9

文献：Romero, F. Anthony; Vodonick, Steven M.; Criscione, Kevin R.; McLeish, Michael J.; Grunewald, Gary L. Journal of Medicinal Chemistry, 2004 , vol. 47, # 18 p. 4483 - 4493

460-37-7 96650-83-8 ~% 460-39-9

文献：Warner-Lambert Company Patent: US4960815 A1, 1990 ;

406-91-7 ~% 460-39-9

文献：Hoffman, Robert V.; Shankweiler, Jean M. Journal of the American Chemical Society, 1988 , vol. 110, # 12 p. 4019 - 4022

107-95-9 ~% 460-39-9

文献：Biggi,G.; Pietra,F. Journal of the Chemical Society [Section] B: Physical Organic, 1971 , p. 44 - 48

460-35-5 ~% 460-39-9

文献：Dickey et al. Industrial and Engineering Chemistry, 1956 , vol. 48, p. 209,212

347190-33-4 ~% 460-39-9

文献：Dickey et al. Industrial and Engineering Chemistry, 1956 , vol. 48, p. 209,212

75-38-7 100-97-0 ~% 460-39-9

文献：Podol'skii,A.V. et al. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1966 , p. 1518 - 1523 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1966 , p. 1575 - 1581

上下游产品

上游产品  8
460-75-3 460-37-7 406-91-7 107-95-9
460-35-5 347190-33-4 75-38-7 100-97-0
下游产品  0

海关

海关编码	2921199090
中文概述	2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%