460-35-5

• 常用中文名：1-氯-3,3,3-三氟丙烷
• 常用英文名：3-chloro-1,1,1-trifluoropropane
• CAS号：460-35-5
• 分子式：C₃H₄ClF₃
• 分子量：132.512
• 相关类别： 有机原料 有机氟化合物 氟丙烷系列
• 发布时间：2018-02-23 08:00:00
• 更新时间：2026-07-01 10:38:31
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名称

• 中文名: 3-氯-1,1,1-三氟丙烷
• 英文名: 3-Chloro-1,1,1-trifluoropropane
• 中文别名: 丙烷,3-氯-1,1,1-三氟; 氯三氟丙烷; 1-丙炔,1-氯-3,3,3-三氟; 1,1,1-三氟-3-氯丙烷; 单氯三氟丙烷; 1-氯-3,3,3-三氟-丙-1-炔; 1-氯-3,3,3-三氟丙-1-炔
• 英文别名: 3,3,3-TRIFLUORO-1-CHLOROPROPANE; oro-1,1,1-trifL; MFCD00069094; 3-chloro-1,1,1-trifluoro-propan; 3-CHLORO-1,1,1-TRIFLUOROPROPANE; propane,3-chloro-1,1,1-trifluoro; Freon; 1-Propyne, 1-chloro-3,3,3-trifluoro; 1,1,1-Trifluoro-3-chlorpropane; EINECS 207-307-0; Monochlorotrifluoropropane; TRIFLUORO-3-CHLOROPROPANE; CHLOROTRIFLUOROPROPANE; 3,3,3-Trifluorochloropropane; 1-TRIFLUOROPROPANE; 3-CHLORO-1,1,1-TRIFLUOROPROPANE ISO 9001：2015 REACH; 1-CHLORO-3,3,3-TRIFLUOROPROPANE; R253fb; 3,3,3-Trifluoropropyl chloride; CF3CH2CH2Cl; 1,1,1-Trifluoro-3-chloropropane; HCFC 253fb; freon253; HCFC-253fb

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 44.1±8.0 °C at 760 mmHg
• 熔点: -106.2℃
• 分子式: C₃H₄ClF₃
• 分子量: 132.512
• 闪点: -6.8±10.4 °C
• 精确质量: 131.995361
• LogP: 1.55
• 蒸汽压: 380.2±0.1 mmHg at 25°C
• 折射率: 1.324
• 储存条件: 室温，密封

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TX6200000 CHEMICAL NAME : Propane, 3-chloro-1,1,1-trifluoro- CAS REGISTRY NUMBER : 460-35-5 BEILSTEIN REFERENCE NO. : 1734941 LAST UPDATED : 199701 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C3-H4-Cl-F3 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1800 mg/m3/2H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 62 mg/kg TOXIC EFFECTS : Behavioral - sleep Behavioral - somnolence (general depressed activity) Behavioral - ataxia REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/m3/2H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2300 mg/m3/2H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1062 mg/kg/30W-I TOXIC EFFECTS : Behavioral - alteration of classical conditioning REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1062 mg/kg/30W-I TOXIC EFFECTS : Blood - change in clotting factors Blood - other changes REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 22-36
• 安全声明 (欧洲): 23-24/25-26
• 海关编码: 2903791090

合成路线

上下游产品

上游产品  10
75-72-9 421-07-8 1070-78-6 338-75-0
677-21-4 107-94-8 819-00-1 460-37-7
7783-56-4 7647-01-0
下游产品  10
460-39-9 431-21-0 460-69-5 7125-84-0
677-21-4 2240-88-2 682-37-1 690-96-0
421-07-8 460-66-2

海关

海关编码	2903791090
中文概述	2903791090 其他仅含氟和氯的甲烷、乙烷及丙烷的卤化衍生物。监管条件:14xy(进口许可证,出口许可证,出口许可证(加工贸易),出口许可证(边境小额贸易))。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
监管条件	1.进口许可证 4.出口许可证 x.出口许可证(加工贸易) y.出口许可证(边境小额贸易)
Summary	2903791090 halogenated derivatives of methane, ethane or propane (hcfcs)only with fluorine and chlorine。supervision conditions:14xy(import license,export license,export license,export license)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%