79617-89-3

• 常用中文名：4-(3,4-二氯苯基)-1,2,3,4-四氢-N-甲基-1-萘胺盐酸盐
• 常用英文名：cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
• CAS号：79617-89-3
• 分子式：C₁₇H₁₈Cl₃N
• 分子量：342.690
• 发布时间：2018-06-12 08:59:16
• 更新时间：2024-01-04 11:19:10
• 舍曲林中间体

名称

• 中文名: 舍曲林碱
• 英文名: cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
• 中文别名: 4-(3,4-二氯苯基)-1,2,3,4-四氢-N-甲基-1-萘胺盐酸盐
• 英文别名: cis-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride; [4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]methylamine hydrochloride; 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1); cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthaleneamine hydrochloride; 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride (1:1); 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride; cis(1S,1R)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-terahydro-1-(2H)-napthalenamine hydrochloride; (+/-)-sertraline hydrochloride; 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (1:1); 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINEHYDROCHLORIDE; Sertraline Hydrochloride Racemic Mixture (25 mg) (1:1 mixture of (1S,4S) and (1R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride)

物化性质

• 沸点: 443.8ºC at 760 mmHg
• 熔点: 275-277ºC
• 分子式: C₁₇H₁₈Cl₃N
• 分子量: 342.690
• 闪点: 222.2ºC
• 精确质量: 341.050476
• PSA: 12.03000
• LogP: 6.37250

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302-H412
• 警示性声明: P273
• 危险品运输编码: NONH for all modes of transport

合成路线

140631-53-4 ~78% 79617-89-3

文献：UNICHEM LABORATORIES LIMITED Patent: WO2007/119247 A2, 2007 ; Location in patent: Page/Page column 23 ;

261776-41-4 ~% 79617-89-3

文献：WO2007/124920 A1, ; Page/Page column 14-15 ;

79836-45-6 ~% 79617-89-3

文献：US2006/14838 A1, ; Page/Page column 2-3 ;

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