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553-84-4

553-84-4结构式
553-84-4结构式
  • 常用中文名:紫苏酮
  • 常用英文名:1-Pentanone,1-(3-furanyl)-4-methyl-
  • CAS号:553-84-4
  • 分子式:C10H14O2
  • 分子量:166.21700
  • 相关类别: 研究领域 感染
  • 发布时间:2018-12-30 09:14:52
  • 更新时间:2024-01-07 18:22:04
  • 紫苏酮是一种天然存在的外源化合物。紫苏酮被肺中的肺P450细胞色素酶激活,导致严重的肺损伤和弥漫性肺水肿[1]。

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中文名 1-呋喃-3-基-4-甲基-1-戊酮
英文名 1-(furan-3-yl)-4-methylpentan-1-one
英文别名 Perilla ketone
1-furan-3-yl-4-methyl-pentan-1-one
Purple mint plant extract
描述 紫苏酮是一种天然存在的外源化合物。紫苏酮被肺中的肺P450细胞色素酶激活,导致严重的肺损伤和弥漫性肺水肿[1]。
相关类别
参考文献

[1]. Alan R Doster, et al. Bovine atypical interstitial pneumonia. Vet Clin North Am Food Anim Pract. 2010 Jul;26(2):395-407.

密度 0.976g/cm3
沸点 224.4ºC at 760mmHg
分子式 C10H14O2
分子量 166.21700
闪点 96.8ºC
精确质量 166.09900
PSA 30.21000
LogP 2.89850
折射率 1.465
储存条件 2-8°C, 密封, 干燥, 惰性气体

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SA8935000
CHEMICAL NAME :
1-Pentanone, 1-(3-furanyl)-4-methyl-
CAS REGISTRY NUMBER :
553-84-4
BEILSTEIN REFERENCE NO. :
0114624
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H14-O2
MOLECULAR WEIGHT :
166.24
WISWESSER LINE NOTATION :
T5OJ CV2Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 197,573,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 197,573,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
106 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 60,248,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
14 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 60,248,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
13700 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 60,248,1985
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 45,300,1978

海关编码 2932190090
海关编码 2932190090
中文概述 2932190090 其他结构上有非稠合呋喃环化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%