100442-33-9

• 常用中文名：2,N-二甲基-N-(3,3-二苯基丙基)-1-氨基-2-丙醇
• 常用英文名：1-(3,3-Diphenyl-N-methylpropylamino)-2-methyl-2-propanol
• CAS号：100442-33-9
• 分子式：C₂₀H₂₇NO
• 分子量：297.435
• 发布时间：2018-02-17 08:00:00
• 更新时间：2026-07-08 12:59:27

名称

• 中文名: 2,N-二甲基-N-(3,3-二苯基丙基)-1-氨基-2-丙醇
• 英文名: 2,N-Dimethyl-N-(3,3-Diphenylpropyl)-1-Amino-2-Propanol
• 中文别名: 乐卡地平杂质12; 盐酸乐卡地平中间体2; 1-((3,3-二苯基丙基)(甲基)氨基)-2-甲基丙-2-醇; 乐卡地平侧链; 1-[(3,3-二苯基丙基)甲氨基]-2-甲基-2-丙醇; 1-[(3,3-二苯基丙基)(甲基)氨基]-2-甲基-2-丙醇; 盐酸乐卡地平/乐卡地平侧链; 盐酸乐卡地平杂质N; 乐卡地平侧链醇; 乐卡地平的IMP 1; 乐卡地平侧链对照品; 2,N-二甲基-N-(3,3-二苯基丙基)-1-氨基-2-丙醇(乐卡地平侧链); 盐酸乐卡地平侧链/乐卡地平侧链; N-二甲基-N-(3,3-二苯基丙基)-1-氨基-2-丙醇
• 英文别名: 2,N-DiMethyl-N-(3,3-diphenipropyl)-1-amino-2-propyl alcohol; N,2-Dimethyl-3,3- diphenylpropylamine-2- propanol; 1-((3,3-diphenylpropyl)(Methyl)amino)-2-Methylpropan-2-ol; Le Cdipine Side Chain Reference; LERCANIDIPINEBRANCH; 2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol (100-9); N N DiMehyl AcetaMide; N-Dimethyl-N-(3; IMP 1 of Lercanidipine; (1S,2R)-N-BENZYL-2-AMINO-1,50-DIPHENYLETHANOL; 2,N-DIMETHYL-N-(3,3-DIPHENYLPROPYL)-1-AMINO-2-PROPANOL; 1-[(3,3-Diphenylpropyl)methylamino]-2-methyl-2-propanol; 3-diphenylpropyl)-1-amino-2-propanol; 2,N-dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol (intermediate of lercanidipine); 1-(3,3-DIPHENYL-N-METHYLPROPYLAMINO)-2-METHYL-2-PROPANOL; 2,N-dimethyl-N-(3,3-diphenylproply)-1-amino-2-propanol; MFCD07782118; 2,N-DIMETHYL-N-(3,3-DIPHENYLPROPYL)-1-AMINO-PROPANOL; Lercanidipine side chain; Lercidipine Branch; 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanol >; 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanol; 2,N-Dimethyl-N-(3,3-Diphenylpr; QX1&1&1N1&2YR&R; 2-Methyl-1-[N-methyl-N-(3,3-diphenylpropyl)amino]propan-2-ol; TIANFU CHEM--2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol; 2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propyl alcohol; 2,N-Dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol Hydrochloride; 2-Propanol,1-[(3,3-diphenylpropyl)methylamino]-2-methyl; Lecanidipine InterMediate; Lercanidipine Impurity 12; 1-(3,3-diphenyl-N-methylpropylamino)-2-methyl-2-propanol (intermediate of lercanidipine); 1-chloro-2-methylpropan-2-yl 3-oxobutanoate; Le cd horizon side chain; 2,N-DIMEHYL-n(3,3-DIPHENYLPROPYL)-1-amino-2-propanol

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 428.9±40.0 °C at 760 mmHg
• 分子式: C₂₀H₂₇NO
• 分子量: 297.435
• 闪点: 164.7±23.9 °C
• 精确质量: 297.209259
• PSA: 23.47000
• LogP: 4.59
• 外观性状: 淡黄色油性液体
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.556
• 储存条件: 2-8°C
• 稳定性: Normal temperature and pressure

安全

• 危害码 (欧洲): Xi
• 海关编码: 2922199090

合成路线

558-42-9 28075-29-8 ~81% 100442-33-9

文献：Leonardi, Amedeo; Motta, Gianni; Pennini, Renzo; Testa, Rodolfo; Sironi, Giorgio; Catto, Alberto; Cerri, Alberto; Zappa, Marco; Bianchi, Giorgio; Nardi, Dante European Journal of Medicinal Chemistry, 1998 , vol. 33, # 5 p. 399 - 420

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海关

海关编码	2922199090
中文概述	2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%