252977-54-1

• 常用中文名：7-(叔丁基)-6-氯-3-(2-氟苯基)-[1,2,4]三唑并[4,3-b]哒嗪
• 常用英文名：7-(tert-Butyl)-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
• CAS号：252977-54-1
• 分子式：C₁₅H₁₄ClFN₄
• 分子量：304.75000
• 发布时间：2017-04-02 16:04:15
• 更新时间：2024-01-10 08:36:19

名称

• 中文名: 7-(叔丁基)-6-氯-3-(2-氟苯基)-[1,2,4]三唑并[4,3-b]哒嗪
• 英文名: 7-tert-butyl-6-chloro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
• 英文别名: 6-chloro-7-(1,1-dimethylethyl)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine; QC-4197; 6-chloro-7-(1,1-dimethyleth-1-yl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine

物化性质

• 分子式: C₁₅H₁₄ClFN₄
• 分子量: 304.75000
• 精确质量: 304.08900
• PSA: 43.08000
• LogP: 3.88130
• 储存条件: 2-8°C

合成路线

22808-29-3 446-24-2 ~44% 252977-54-1

文献：Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

252977-55-2 393-52-2 ~69% 252977-54-1

文献：Merck Sharp and Dohme Ltd. Patent: US6630471 B1, 2003 ;

22808-29-3 51859-98-4 ~44% 252977-54-1

文献：Carling, Robert W.; Madin, Andrew; Guiblin, Alec; Russell, Michael G. N.; Moore, Kevin W.; Mitchinson, Andrew; Sohal, Bindi; Pike, Andrew; Cook, Susan M.; Ragan, Ian C.; McKernan, Ruth M.; Quirk, Kathleen; Ferris, Pushpinder; Marshall, George; Thompson, Sally Ann; Wafford, Keith A.; Dawson, Gerard R.; Atack, John R.; Harrison, Timothy; Castro, Jose L.; Street, Leslie J. Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7089 - 7092

上下游产品

上游产品  5
22808-29-3 446-24-2 252977-55-2 393-52-2
51859-98-4
下游产品  0