146943-43-3

• 常用中文名：N-(4-(2-(2-氨基-4-氧代-4,7-二氢-3H-吡咯并[2,3-d]嘧啶-5-基)乙基)苯甲酰基)-L-谷氨酸二乙酯
• 常用英文名：PEMETREXED DIETHYL ESTER (L-GLUTAMIC ACID, N-[4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)ETHYL]BENZOYL]-, 1,5-DIETHYL ESTER )
• CAS号：146943-43-3
• 分子式：C₂₄H₂₉N₅O₆
• 分子量：483.51700
• 相关类别： 生物化工 氨基酸及其衍生物 谷氨酸类衍生物
• 发布时间：2018-12-30 17:54:13
• 更新时间：2026-08-02 22:06:20

名称

• 中文名: N-(4-(2-(2-氨基-4-氧代-4,7-二氢-3H-吡咯并[2,3-d]嘧啶-5-基)乙基)苯甲酰基)-L-谷氨酸二乙酯
• 英文名: pemetrexed diethyl ester
• 中文别名: 培美曲塞杂质75; N-(2-氨基-6-氧代-3,6-二氢嘧啶-4-基)-4-(3-(2,6-二氨基-4-氧代-1,4-二氢嘧啶-5-基)-4 -硝基丁基)苯甲酰胺(培美曲塞杂质); N-(4-[2-(2-氨基-4,7-二氢-4-氧-1H-吡咯[2,3-D]嘧啶-5-基)乙基]苯甲酰)-L-谷氨酸二乙酯; N-(4-(2-(2-氨基-4-氧代-4,7-二氢-3H-吡咯并[2,3-D]嘧啶-5-基)乙基)苯甲酰基)-L-谷氨酸二乙酯
• 英文别名: (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, 1,5-diethyl ester; Pemetrexed Impurity 20(Pemetrexed Diethyl Ester); N-{4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-EL)ETHYL]BENZOYL}-L-GLUTAMICACID1,5-DIETHYLESTER; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester //BP; PeMetrexed Diethyl Ester; Famitinib Impurity 2; l-glutamic acid,n-[4-[2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-,1,5-diethyl ester; (s)-diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; PeMetrexed diethyl ester (L-GlutaMic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-, 1,5-diethyl ester ); n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]- l-glutamic acid diethyl ester; (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate (Pemetrexed Disodium Impurity); Diethyl N-[4-{2-(2-amino-4-hydroxypyrrolo[2,3-d]pyrimidin-5-yl)ethyl}-benzoyl]-L-glutamate

物化性质

• 密度: 1.38
• 熔点: 84-86 °C
• 分子式: C₂₄H₂₉N₅O₆
• 分子量: 483.51700
• 精确质量: 483.21200
• PSA: 169.26000
• LogP: 2.59550

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