343-55-5

• 常用中文名：双氯西林钠
• 常用英文名：Dicloxacillin Sodium
• CAS号：343-55-5
• 分子式：C₁₉H₁₇Cl₂N₃NaO₅S
• 分子量：493.31600
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-08-29 17:20:36
• 更新时间：2026-08-06 17:23:08
• Dicloxacillin sodium 是一种窄谱的、β 内酰胺族青霉素抗生素。Dicloxacillin sodium 可有效抵抗产生β 内酰胺酶的细菌,如 Staphylococcus aureus。

名称

• 中文名: 双氯西林钠
• 英文名: dicloxacillin sodium
• 中文别名: 双氯西林钠盐
• 英文别名: Pathocil; 4-Thia-1-azabicyclo3.2.0htane-2-cboxylic acid, -(2,6-dichlorophenyl)-5-methyl-4-isoxazolylcbonylamino-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R); Dichlor-Stapenor; EINECS 206-444-3; (2S,5β)-6α-[[[3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]htane-2β-cboxylic acid sodium salt; Veracillin; Diclocil; VERACILLIN; BRL1702; Constaphyl; Noxaben; Pen-Sint; 6-(3-(2,6-dichlorophenyl)-4-thia-1-azabicyclo(3.2.0)htane-2-cboxylic aci; Brispen; Dicloxacillin sodiuM hydra; BRL1702 Sodium; (2S,5R,6R)-6-[[[3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]htane-2-cboxylic acid sodium salt; sodiuM (2S,5R,6R)-6-(3-(2,6-dichlorophenyl)-5-Methylisoxazole-4-cboxaMido)-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]htane-2-cboxylate; 5-methyl-4-isoxazolecboxamido)-3,3-dimethyl-7-oxo-, monosodium salt, monohyd; sodium [2S-(2alpha,5alpha,6beta)]-6-[[[3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]htane-2-cboxylate [3.2.0]; Dicloxacillin Sodium Salt; Stampen; Dicloxacillin sodium hydrate; 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl penicillin sodium monohydrate; Dynapen; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, monosodium salt (8CI); Sodium [3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]penicillin; 4-Thia-1-azabicyclo[3.2.0]htane-2-cboxylic acid, 6-[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecboxamido]-3,3-dimethyl-7-oxo-, monosodium salt (8CI); 4-Thia-1-azabicyclo[3.2.0]htane-2-cboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S,5R,6R); Dycill; 4-Thia-1-azabicyclo[3.2.0]htane-2-cboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]; Dicloxacilline SodiumQ: What is Dicloxacilline Sodium Q: What is the CAS Number of Dicloxacilline Sodium Q: What is the storage condition of Dicloxacilline Sodium; sodium [2S-(2alpha,5alpha,6beta)]-6-[[[3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]htane-2-cboxylate [3.2.0]

物化性质

• 分子式: C₁₉H₁₇Cl₂N₃NaO₅S
• 分子量: 493.31600
• 精确质量: 492.01600
• PSA: 138.04000
• LogP: 3.53090
• 外观性状: 粉末
• 储存条件: -20℃

生物活性

• 描述: Dicloxacillin sodium 是一种窄谱的、β 内酰胺族青霉素抗生素。Dicloxacillin sodium 可有效抵抗产生β 内酰胺酶的细菌,如 Staphylococcus aureus。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Miranda-Novales G, et al. In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. strains. Ann Clin Microbiol Antimicrob. 2006 Oct 12;5:25.

合成路线

551-16-6 4462-55-9 ~% 343-55-5

文献：WO2012/164355 A1, ; Page/Page column 10 ;

3919-76-4 ~% 343-55-5

文献：WO2012/164355 A1, ;

83-38-5 ~% 343-55-5

文献：WO2012/164355 A1, ;

上下游产品

上游产品  4
551-16-6 4462-55-9 3919-76-4 83-38-5
下游产品  0