80965-09-9

• 常用中文名：(1RS)-5-苯甲酰基-2,3-二氢-1H-吡咯嗪-1-甲酸甲酯(酮咯酸甲酯)
• 常用英文名：methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
• CAS号：80965-09-9
• 分子式：C₁₆H₁₅NO₃
• 分子量：269.29500
• 发布时间：2017-06-11 09:42:56
• 更新时间：2026-07-01 18:40:52

名称

• 中文名: (1RS)-5-苯甲酰基-2,3-二氢-1H-吡咯嗪-1-甲酸甲酯(酮咯酸甲酯)
• 英文名: methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
• 中文别名: 酮咯酸杂质11; 去氧肾上腺素酮咯酸溶液杂质C; 酮洛酸氨丁三醇杂质H; 酮咯酸氨丁三醇杂质H; 酮洛酸杂质H; 酮咯酸氨丁三醇杂质I对照品; 酮咯酸甲酯; 酮咯酸H; 酮咯酸氨丁三醇杂质H 80-9; 5-苯甲酰基-2,3-二氢-1H-吡咯嗪-1-羧酸甲酯 (酮咯酸杂质); 酮咯酸杂质08; 酮咯酸表观性H; 酮咯酸杂质10(酮咯酸杂质H); 酮咯酸杂质H; 酮咯酸氨丁三醇中间体6杂质7
• 英文别名: methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-cboxylate; 5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid methyl ester; Ketorolac Tromethamine Impurity I; Ketorolac Impurity 10（ Impurity H）; Methyl (1RS)-5-Benzoyl-2,3-dihydro; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid methyl ester; methyl 5-benzoyl-1,2-dihydro-3H-pyrrol[1,2-a]pyrrole-1-carboxylate; Ketorolac Trometamol Impurity H; Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-cboxylate (Ketorolac Impurity); 2,2'-(1,3-phenylene)dipropionic acid; Ketorolac tromethamine intermediate 6 Impurity 7; 1H-Pyrrolizine-1-carboxylic acid,5-benzoyl-2,3-dihydro-,methyl ester; Ketorolac Impurity H (Ketorolac Methyl Ester); 5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-cboxylic acid methyl ester; (+/-)-ketorolac methyl ester; 1H-Pyrrolizine-1-cboxylic acid, 5-benzoyl-2,3-dihydro-, methyl ester; Ketorolac Impurity 11; Methyl (1RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-cboxylate (Ketorolac Methyl Ester); Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-cboxylate, racemic; Ketorolac Trometamol Imp. H : Methyl (1RS)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-cboxylate; Ketolotritol impurity H; methyl 5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate

物化性质

• 分子式: C₁₆H₁₅NO₃
• 分子量: 269.29500
• 精确质量: 269.10500
• PSA: 48.30000
• LogP: 2.37940

合成路线

189696-36-4 ~61% 80965-09-9

文献：Ohmeda Pharmaceutical Products Division Inc. Patent: US5621115 A1, 1997 ;

74103-06-3 ~% 80965-09-9

文献：Syntex (U.S.A.) Inc. Patent: US4089969 A1, 1978 ;

80965-00-0 ~% 80965-09-9

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

611-74-5 ~% 80965-09-9

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

83727-08-6 ~% 80965-09-9

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

67-56-1 74103-06-3 ~74% 80965-09-9

文献：McTiernan, Christopher D.; Fasciani, Chiara; Gonzalez-Bejar, Maria; Roca-Sanjuan, Daniel; Alarcon, Emilio I.; Netto-Ferreira, Jose Carlos MedChemComm, 2013 , vol. 4, # 12 p. 1619 - 1622

80965-05-5 ~% 80965-09-9 80965-08-8

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

80965-03-3 ~% 80965-09-9

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

80965-04-4 ~% 80965-09-9

文献：Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

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74103-06-3 80965-00-0 611-74-5 83727-08-6
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