16679-58-6

• 常用中文名：去氨加压素
• 常用英文名：(Deamino-Cys1,D-Arg8)-Vasopressin acetate salt
• CAS号：16679-58-6
• 分子式：C₄₆H₆₄N₁₄O₁₂S₂
• 分子量：1069.217
• 相关类别： 原料药 泌尿系统用药 尿崩症用药
• 发布时间：2018-08-03 09:34:20
• 更新时间：2026-06-29 20:00:38
• Desmopressin(DDAVP)是抗利尿激素精氨酸加压素的合成类似物。

名称

• 中文名: 去氨加压素
• 英文名: desmopressin
• 中文别名: DIVBIO/深创生物，醋酸去氨加压素，Desmopressin; 药典对照品/去氨加压素/C1A; [去氨基-CYS1, D-G8]- 加压素; 醋酸去氨加压素; 去氨加压素;去氨压素; 缩宫素/去氨加压素,确认混合物/C1A; 去氨加压素-[D5]/精确称量; 去氨加压素 标准品; 氘5-去氨加压素; 醋酸去氨加压素(DDAVP); 去氨加压素中间体; 醋酸去氨压素, (HPLC); 去氨加压素-多肽原料委托; 醋酸去氨压素; 醋酸去氨压素/去氨加压素; 去氨压素; 去氨加压素-多肽制剂一致性评价; 去氨加压素(DDAVP); 去氨加压素 三氟乙酸盐; 的斯加压素; DIVBIO/深创生物,醋酸去氨加压素,Desmopressin; 醋酸去氨加压素 DESMOPRESSIN; 去氨加压素/C1A; 去氨加压素(醋酸盐)
• 英文别名: D5-Desmopressin; DESAMINO-[D-G8]VASOPRESSIN; DESAMINO-[D-ARG8]VASOPRESSIN; DESMOPRESSIN,HUMAN; 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-G-GLY-NH2; [DEAMINO1, DG8] VASOPRESSIN; [deamino-Cys1, D -g8]-Vasopressin acetate salt hydrate; 3-Mercaptopropionyl-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys-L-Pro-D-g-Gly-NH2; M.W. 1069.22 C46H64N14O12S2; [DEAMINO-CYS1,D-ARG8]-VASOPRESSIN; MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2(DISULFIDE BRIDGE,MAP1-CYS6); Desmopressin-D5 TFAQ: What is Desmopressin-D5 TFA Q: What is the CAS Number of Desmopressin-D5 TFA Q: What is the storage condition of Desmopressin-D5 TFA Q: What e the applications of Desmopressin-D5 TFA; Desmopressin; MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-G-GLY-NH2(DISULFIDE BRIDGE, MAP1-CYS6); [Deamino-Cys1, D-g8]-Vassopressin; Desmopresina, Desmopressine, Desmopressinum; MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-G-GLY-NH2; Desmopressin Trifluoroacetate; Desmopressin (DDAVP); DDAVP,HUMAN; Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspaginyl-L-cysteinyl-L-prolyl-D-ginyl-, cyclic (1→5)-disulfide; MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-G-GLY-NH2; DDAVP, HUMAN; Oxytocin Impurity 13 (Desmopressin); 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-g-Gly-NH2 acetate salt (Disulfide bond); Mep(mercaptopropionic acid)-YFQNCPdRG-NH2; Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-ginine; 1-Desamino-8-D-ginine vasopressin; C46H64N14O12S2; Desmopressin acetate, (HPLC); N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl); [Deamino1,Dg8] Vasopressin (dDAVP) Desmopressin; DESMOPRESSIN ACETATE PH. EUR; Desmopressin Acetate(net); Desmopressin CRS; esmopressin; Desmopressin //BP; DESMOPRESSIN, HUMAN; 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-G-GLY-OH (DISULFIDE BRIDGE: ); (Deamino-Cys,D-g)-Vasopressin acetate salt; [deamino-cys1, d-g8]-vasopressin acetate hydrate; DDAVP; [deamino-Cys; [DEAMINO-CYS1, D-G8]-VASOPRESSIN; (Deamino-Cys1,D-g)-Vasopressin; (Deamino-Cys1,D-g8)-Vasopressin acetate salt 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-g-Gly-NH2 acetate salt (Disulfide bond); [DEAMINO1,DARG8] VASOPRESSIN; 3-MERCAPTOPROPIONYL-YFQNRG (DISULFIDE BRIDGE: ); DESMOPRESSIN ACETATE PH. EUR.; Iloprost Impurity 8; Adiuretin-SD; 1-{[(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide; DESMOPRESSIN; Octostim; MINIRIN

物化性质

• 密度: 1.6±0.1 g/cm3
• 分子式: C₄₆H₆₄N₁₄O₁₂S₂
• 分子量: 1069.217
• 精确质量: 1068.427002
• PSA: 486.01000
• LogP: -5.82
• 折射率: 1.713

生物活性

• 描述: Desmopressin(DDAVP)是抗利尿激素精氨酸加压素的合成类似物。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 血管加压素受体
  研究领域 >> 代谢疾病
  天然产物 >> 其他
  多肽产品
• 参考文献:

  [1]. Vande Walle J, Stockner M, Raes A, N?rgaard JP. Desmopressin 30 years in clinical use: a safety review. Curr Drug Saf. 2007 Sep;2(3):232-8.

  [2]. Franchini M, Zaffanello M, Lippi G. The use of desmopressin in mild hemophilia A. Blood Coagul Fibrinolysis. 2010 Oct;21(7):615-9.

  [3]. Sánchez-Luceros A, Meschengieser SS, Woods AI et al. Biological and clinical response to desmopressin (DDAVP) in a retrospective cohort study of children with low von Willebrand factor levels and bleeding history. Thromb Haemost. 2010 Nov;104(5):984-9.

  [4]. Alonso DF, Ripoll GV, Garona J et al. Metastasis: recent discoveries and novel perioperative treatment strategies with particular interest in the hemostatic compound desmopressin. Curr Pharm Biotechnol. 2011 Nov;12(11):1974-80.

  [5]. Tsukamoto I. Recent patenting activities in the discovery and development of vasopressin V2 receptor agonists. Expert Opin Ther Pat. 2012 Jun;22(6):579-86.

安全

• 海关编码: 2937190090

海关

海关编码	2937190090