1951-26-4

• 常用中文名：2-丁基-3-(3,5-二碘-4-羟基苯甲酰基)苯并呋喃
• 常用英文名：2-BUTYL-3-(3,5-DIIODO-4-HYDROXYBENZOYL) BENZOFURAN
• CAS号：1951-26-4
• 分子式：C₁₉H₁₆I₂O₃
• 分子量：546.13700
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-11-24 11:14:31
• 更新时间：2026-07-06 13:08:30
• 【用途一】
  用作盐酸胺碘酮中间体
  【用途二】
  乙胺碘呋酮的中间体。

名称

• 中文名: 2-丁基-3-(3,5-二碘-4-羟基苯甲酰)苯并呋喃
• 英文名: 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran
• 中文别名: (2-丁基苯并呋喃-3-基)(4-羟基-3,5-二碘苯基)甲酮; 2-丁基-3-(3,5-二碘-4-羟基苯甲酰)苯并呋喃 (盐酸胺碘酮); 盐酸胺碘酮杂质D; 胺碘酮杂质4(胺碘酮杂质D)(胺碘酮RELATEDCOMPOUNDD); 胺碘酮相关物质D 标准品; 胺碘酮相关物质D; 胺碘酮杂质F; 盐酸胺碘酮杂质Ⅱ; 2-丁基-3-(4-羟基-3,5-二碘苯甲酰基)苯并呋喃; 碘代物; 胺碘酮相关化合物D; 胺碘酮杂质D; 2-丁基-3-(3,5-二碘-4-羟基苯甲酰)苯并呋喃标准品; 盐酸胺碘酮 碘代; 盐酸胺碘酮D; 盐酸胺碘酮杂质D 标准品; 盐酸胺碘酮杂质Ⅱ（2-丁基苯并呋喃-3-基）（4-羟基-3，5-二碘苯基）-甲酮; (2-丁基苯并呋喃-3-基)(3,5-二碘-4-羟基苯基)(甲)酮; 2-丁基-3-(5,6-二碘-4-羟基苯甲酰基)苯并呋喃; 盐酸胺碘酮杂质Ⅰ((2-丁基苯并呋喃-3-基)(4-羟基-3,5-二碘苯基)-甲酮); 2-BUTYL-3-(4-HYDROXY-3,5-DIIODOBENZOYL)BENZOFURAN 2-丁基-3-(4-羟基-3,5-二碘苯甲酰基)苯并呋喃
• 英文别名: 2-BUTYL-3-(3,5-DIIODO-4; Amiodon Hydrochloride ImpurityⅡ：2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran; 2-n-Butyl-3-(3,5-diiodo-4-hydroxy benzoyl) benzofuran; Amiodarone Impurity 4; (2-Butyl-benzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)-methanone; 2-BUTYL-3415-D10DO-4-HYDROXYBENZOYL) BENZOFURAN; AMIODONE IMP D; Amiodone Related Compound 2; Di-iodo Amiodone(Amiodone impurity); 2,3,DIIODO BENZO FURAN; Amiodone Impurity D/ Amiodone Related Compound D; (4-Hydroxy-3,5-Diiodo)-Benzoyl-2-Butyl benzofuran; 2-butyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl ketone; Methanone, (2-butyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl); IMp. D : (2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)Methanone; Amiodone Impurity 4（Amiodone Impurity D）（Amiodone Related Compound D ）; 2-BUTYL-3-(3,5-DIIODO-4-HYDROXY BENZOYL) BENZOFURANE; (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone; 2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran###2-BUTYL-3-(3,5-DIIODO-4-HYDROXY BENZOYL)BENZOFURANE 1-4; Amiodone impurity 4/Amiodone Impurity D/2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran; 2-BUTYL-3-(3,5-DIIODO-4-HYDROXY BENZOYL)BENZOFURAN; 3,5-diiodo-4-hydroxy benzoyl] t bBn fu3an; d . (2-b utylb e nzof ura n-3-yl)(4-h yd roxy-3,5-d i i od oph e nyl)me th a none; 2-Butyl-3-(3',5-Diiodo-4-Hydroxybensoyl)-Benzofuran; EINECS -7; 2-BUTYL-3-(4-HYDROXY3,5-DIIODOBENYL)-BENZOFURAN; EINECS 217-773-7; Amiodone Related Compound D (20 mg) ((2-butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone); 2-BUTYL-3-(3',5'-DIIODO-4-HYDROXYBENZONYL)BENZOFURAN; Amiodone impurity -D; 6-(3-hydroxybutan-2-yl)-5-(hydroxymethyl)-4-methoxy-2-pyranone; MFCD02675787; Amiodarone Related Compound D; 2-Butyl-3-(3,5-Diido-4-HydroxyBenzoyl)Benzofuran; (2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone; Amiodone Hydrochloride Impurity Ⅱ; Amiodone Hydrochloride Impurity Ⅰ; 2-Butyl-3-(4-hydroxy-3,5-diiodobenzoyl)benzofuran; Amiodone Related Compound D ((2-butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone); 3-(4-hydroxy-3,5-diiodo)-benzoyl-2-butylbenzofuran; 2-(n-Butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl) methanone; 2-Buty-(3,5-diiodo-4-hydroxy-benzoy1)benzofuran; 2-Butyl-3-benzofuranyl3,5-diiodo-4-hydroxyphenylketone; 2-butyl-3-(3,5-diiod-hydrobenzoyl)benzofuran; AMiodone IMpurity D; Amiodone Related Compound D; Amiodone Impurity DQ: What is Amiodone Impurity D Q: What is the CAS Number of Amiodone Impurity D Q: What is the storage condition of Amiodone Impurity D Q: What e the applications of Amiodone Impurity D; 2-Butyl-3-(3,5-Diiodo-4-hydroxy; (2-Butylbenzofuran-3-yl)(4-hydroxy; Amiodone Hydrochloride Impurity D; 2-BUTYL-3-(3',5-DIIODO-4-HYDROXYBENZONYL)-BENZOFURAN; (2-butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone; (2-Butyl-benzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)-methanone（Amiodone Hydrochloride）; (2-butyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-methanone; 2-Butyl-3-(3,5-Diodo-4-Hydroxybenzoyl) Benzofuran

物化性质

• 密度: 1.864
• 沸点: 536.8ºC at 760 mmHg
• 熔点: 142-144ºC
• 分子式: C₁₉H₁₆I₂O₃
• 分子量: 546.13700
• 闪点: 278.4ºC
• 精确质量: 545.91900
• PSA: 50.44000
• LogP: 5.92120
• 外观性状: 灰白色固体
• 蒸汽压: 3.89E-12mmHg at 25°C
• 折射率: 1.696
• 储存条件: Refrigerator
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:5

  5.互变异构体数量:4

  6.拓扑分子极性表面积:50.4

  7.重原子数量:24

  8.表面电荷:0

  9.复杂度:432

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

安全

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2932999099

合成路线

52490-15-0 ~% 1951-26-4

文献：European Journal of Clinical Pharmacology, , vol. 55, # 11-12 p. 807 - 814

上下游产品

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海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%