2753-45-9

• 常用中文名：盐酸美贝维林
• 常用英文名：Mebeverine hydrochloride
• CAS号：2753-45-9
• 分子式：C₂₅H₃₆ClNO₅
• 分子量：466.01000
• 相关类别： 原料药 消化系统用药 胃肠解痉药
• 发布时间：2018-06-12 22:48:15
• 更新时间：2026-07-01 23:55:41
• Mebeverine hydrochloride 是β-苯乙胺的衍生物，能够抑制α1 repector的活性，为消化道的一种解痉药。

名称

• 中文名: 盐酸麦皮凡林
• 英文名: Mebeverine Hydrochloride
• 中文别名: 4-[乙基-[2-(4-甲氧苯基)-1-甲基-乙基]氨基]; 甲苯凡林盐酸盐; 4-[乙基-[2-(4-甲氧苯基)-1-甲基-乙基]氨基]丁基3,4-二甲氧基苯甲酸酯盐酸盐; Mebeverine hydrochloride美贝维林盐酸盐; MEBEVERINE盐酸盐; 4-[乙基-[1-(4-甲氧苯基)丙-2-基]氨基]丁基3,4-二甲氧基苯甲酸酯; 盐酸美贝林; 盐酸美贝维林 标准品; 4-{乙基[2-(4-甲氧苯基)-1-甲基乙基]氨基}丁基3,4-二甲氧基苯甲酸酯盐酸盐; 4-[乙基-[1-(4-甲氧基苯基)丙-2-基]氨基]丁基 3,4-二甲氧基苯甲酸酯盐酸盐; 盐酸麦皮凡林,10 MM DMSO 溶液; 美贝维林盐酸盐; 4-[乙基-[1-(4-甲氧苯基)丙-2-基]氨基]丁基3,4-二甲氧基苯甲酸酯盐酸盐
• 英文别名: Mebeverine hydrochloride (Y0002079)Q: What is Mebeverine hydrochloride (Y0002079) Q: What is the CAS Number of Mebeverine hydrochloride (Y0002079); Mebeverine impurity standd; 3,4-dimethoxybenzoic acid 4-[ethyl-[2; 3,4-Dimethoxybenzoic acid 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl] amino]butyl ester HCl; 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butyl 3,4-dimethoxybenzoate hydrochloride; MEBEVERINE HCL TASTE MASK ANULES; Mebeverine hydrochloride, 10 mM in DMSO; 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl 3,4-dimethoxybenzoate,hydrochloride; MEBEVERINE HCL; 4-(ethyl(p-methoxy-alpha-methylphenethyl)amino)butylveratratehydrochloride; Mebeverine hydrochloride: 4-(1RS)-Ethyl2-(4-methoxyphenyl)-1-ethylethylaminobutyl 3,4-dimethoxybenzoate hydrochloride; 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butyl 3,4-dimethoxybenzoate; datalin; Datal Hydrochloride; MEBEVERINE HYDROCHLORIDE; 2-9 Mebeverine hydrochloride; 4-[Ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl 3,4-dimethoxybenzoate hydrochloride; MEBEVERINE; Mebeverine hydrochloride salt; Benzoic acid,3,4-diMethoxy-, 4-[ethyl[2-(4-Methoxyphenyl)-1-Methylethyl]amino]butyl ester,hydrochloride (1:1); veratricacid,4-(ethyl(p-methoxy-alpha-methylphenethyl)amino)butylester,hydr; 3,4-Dimethoxybenzoicacid4-ethyl2-(4-methoxyphenyl)-1-methylethylaminobutylesterhydrochloride; MFCD00867721; MebeverineHydrochloride; Mebeverine (hydrochloride); Colofac Hydrochloride; Mebeverine hydrochloride //BP; 4-{ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino}butyl 3,4-dimethoxybenzoate hydrochloride; Datalin Hydrochloride; EINECS 220-400-0; csag-144; COLOFAC; 3,4-dimethoxybenzoic acid 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl ester hydrochloride; Mebeverine HCL SR Pellets; Mebeverine HydrochlorideQ: What is Mebeverine Hydrochloride Q: What is the CAS Number of Mebeverine Hydrochloride Q: What is the storage condition of Mebeverine Hydrochloride Q: What e the applications of Mebeverine Hydrochloride

物化性质

• 沸点: 543.8ºC at 760mmHg
• 熔点: 105-107ºC
• 分子式: C₂₅H₃₆ClNO₅
• 分子量: 466.01000
• 闪点: 282.7ºC
• 精确质量: 465.22800
• PSA: 57.23000
• LogP: 5.40450
• 外观性状: 粉末
• 蒸汽压: 6.92E-12mmHg at 25°C
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YX5425000 CHEMICAL NAME : Veratric acid, 4-(ethyl(p-methoxy-alpha-methylphenethyl)amino)butyl ester, hydrochloride CAS REGISTRY NUMBER : 2753-45-9 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C25-H35-N-O5.Cl-H MOLECULAR WEIGHT : 466.07 WISWESSER LINE NOTATION : 1OR BO1 DVO4N2&Y1&1R DO1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1540 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2821584 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 17700 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2821584 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,338,1972

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): 36-26
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• RTECS号: YX5425000