1383547-60-1

• 常用中文名：Ingenol disoxate
• 常用英文名：Ingenol disoxate
• CAS号：1383547-60-1
• 分子式：C₂₈H₃₇NO₇
• 分子量：499.596
• 发布时间：2018-06-15 15:14:16
• 更新时间：2025-09-21 15:13:21
• Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphorbia peplus and an inducer of cell death.

名称

• 英文名: Cadazolid
• 英文别名: ingenol disoxate; (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-Dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dien-4-yl 3,5-diethyl-1,2-oxazole-4-carboxylate; 10127; 4-Isoxazolecarboxylic acid, 3,5-diethyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 685.3±55.0 °C at 760 mmHg
• 分子式: C₂₈H₃₇NO₇
• 分子量: 499.596
• 闪点: 368.3±31.5 °C
• 精确质量: 499.256989
• LogP: 5.35
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.604