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1383547-60-1

1383547-60-1 structure
1383547-60-1 structure
  • Name: Ingenol disoxate
  • Chemical Name: Cadazolid
  • CAS Number: 1383547-60-1
  • Molecular Formula: C28H37NO7
  • Molecular Weight: 499.596
  • Create Date: 2018-06-15 15:14:16
  • Modify Date: 2024-01-06 18:36:31
  • Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphorbia peplus and an inducer of cell death.

Name Cadazolid
Synonyms ingenol disoxate
(1S,4S,5S,6R,9S,10R,12R,14R)-5,6-Dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dien-4-yl 3,5-diethyl-1,2-oxazole-4-carboxylate
10127
4-Isoxazolecarboxylic acid, 3,5-diethyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester
Density 1.3±0.1 g/cm3
Boiling Point 685.3±55.0 °C at 760 mmHg
Molecular Formula C28H37NO7
Molecular Weight 499.596
Flash Point 368.3±31.5 °C
Exact Mass 499.256989
LogP 5.35
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.604
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