329182-61-8

• 常用中文名：JR-AB2-011
• 常用英文名：JR-AB2-011
• CAS号：329182-61-8
• 分子式：C₁₇H₁₄Cl₂FN₃OS
• 分子量：398.282
• 发布时间：2021-01-15 12:35:42
• 更新时间：2024-02-27 19:27:49
• JR-AB2-011 is a potent and selective inhibitor of mTORC2 kinase activity. It markedly reduces mTORC2 signaling and IC50 while enhancing apoptotic levels in GBM cells.

名称

• 英文名: 3-(3,4-Dichlorophenyl)-1-(4-fluorophenyl)-1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea
• 英文别名: Urea, N'-(3,4-dichlorophenyl)-N-(4,5-dihydro-5-methyl-2-thiazolyl)-N-(4-fluorophenyl)-; 3-(3,4-Dichlorophenyl)-1-(4-fluorophenyl)-1-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea; N'-(3,4-dichlorophenyl)-N-(4-fluorophenyl)-N-(5-methyl-4,5-dihydro-1,3-thiazol-2-yl)urea

物化性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₁₇H₁₄Cl₂FN₃OS
• 分子量: 398.282
• 精确质量: 397.021881
• LogP: 4.89
• 折射率: 1.660