353512-04-6

• 常用中文名：JAK2-IN-6
• 常用英文名：JAK2-IN-6
• CAS号：353512-04-6
• 分子式：C₁₄H₁₀ClN₃OS₂
• 分子量：335.832
• 发布时间：2021-01-22 09:31:26
• 更新时间：2025-09-19 09:40:26
• JAK2-IN-6, a multiple-substituted aminothiazole derivative, is a potent and selective JAK2 inhibitor with an IC50 of 22.86 μg/mL. JAK2-IN-6 shows no activity against JAK1 and JAK3. JAK2-IN-6 has anti-proliferative effect against cancer cells.

名称

• 英文名: (4-Amino-2-anilino-1,3-thiazol-5-yl)(5-chloro-2-thienyl)methanone
• 英文别名: (4-Amino-2-anilino-1,3-thiazol-5-yl)(5-chloro-2-thienyl)methanone; Methanone, [4-amino-2-(phenylamino)-5-thiazolyl](5-chloro-2-thienyl)-

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 579.6±60.0 °C at 760 mmHg
• 分子式: C₁₄H₁₀ClN₃OS₂
• 分子量: 335.832
• 闪点: 304.3±32.9 °C
• 精确质量: 334.995392
• LogP: 3.06
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.748