287930-73-8

• 常用中文名：4-苄基-2-羟基-吗啉-3-酮
• 常用英文名：4-Benzyl-2-hydroxy-3-morpholinone
• CAS号：287930-73-8
• 分子式：C₁₁H₁₃NO₃
• 分子量：207.226
• 发布时间：2019-02-16 11:58:16
• 更新时间：2026-07-06 11:02:03

名称

• 中文名: 4-苄基-2-羟基-吗啉-3-酮
• 英文名: 4-benzyl-2-hydroxymorpholin-3-one
• 中文别名: 福沙吡坦杂质B; 4-苯甲基-2-羟基吗啉-3-酮*5; 福沙匹坦杂质B; 阿瑞匹坦中间体1; 自产287930-,阿瑞匹坦中间体287-8; 福沙匹坦双葡甲胺SM1-IMPA; 阿瑞匹坦主环的侧链; 4-苄基-2-羟基-吗啉-3-酮(阿瑞匹坦中间体1); 4-苯甲基-2-羟基-吗啉-3-酮; 福沙匹坦杂质23; 阿瑞匹坦关键中间体; 4-羟基-2-苄基-吗啉-3-酮; 4-苄基-2-羟基-吗啉-3-酮(阿瑞匹坦中间体二); 福莫特罗杂质A; 阿瑞匹坦中间体,4-苄基-2-羟基-吗啉-3-酮; 4- 4-苄基-2-羟基-吗啉-3-酮
• 英文别名: 2-Hydroxy-4-(phenylMethyl)-3-Morpholinone; Fosapritant Impurity B; 2-Hydroxy-4-(benzyl)morpholin-3-one; Apritant intermediates，4-Benzyl-2-hydroxy-morpholin-3-one; 4-Benzyl-2-hydroxymorpholin-3-one; 4-Benzyl-2-hydroxy-morpholin-3-one; benzyl lactam lactol; 4- benzyl -2- hydroxymorpholine -3- one; 2-hydroxymorphoL; Apritant Impurity 48; TIANFUCHEM-287-8-High purity 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE factory price; 3-Morpholinone,2-hydroxy-4-(phenylMethyl); Fosapritant Impurity 23; 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 441.7±45.0 °C at 760 mmHg
• 熔点: 136 °C
• 分子式: C₁₁H₁₃NO₃
• 分子量: 207.226
• 闪点: 220.9±28.7 °C
• 精确质量: 207.089539
• PSA: 49.77000
• LogP: 0.27
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.595
• 储存条件: 室温，密封

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

110843-90-8 ~88% 287930-73-8

文献：Nelson, Todd D.; Rosen, Jonathan D.; Brands, Karel M.J.; Craig, Bridgette; Huffman, Mark A.; McNamara, James M. Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8917 - 8920

298-12-4 104-63-2 ~75% 287930-73-8

文献：Brands, Karel M. J.; Payack, Joseph F.; Rosen, Jonathan D.; Nelson, Todd D.; Candelario, Alexander; Huffman, Mark A.; Zhao, Matthew M.; Li, Jing; Craig, Bridgette; Song, Zhiguo J.; Tschaen, David M.; Hansen, Karl; Devine, Paul N.; Pye, Philip J.; Rossen, Kai; Dormer, Peter G.; Reamer, Robert A.; Welch, Christopher J.; Mathre, David J.; Tsou, Nancy N.; McNamara, James M.; Reider, Paul J. Journal of the American Chemical Society, 2003 , vol. 125, # 8 p. 2129 - 2135

104-63-2 ~% 287930-73-8

文献：Brands, Karel M. J.; Payack, Joseph F.; Rosen, Jonathan D.; Nelson, Todd D.; Candelario, Alexander; Huffman, Mark A.; Zhao, Matthew M.; Li, Jing; Craig, Bridgette; Song, Zhiguo J.; Tschaen, David M.; Hansen, Karl; Devine, Paul N.; Pye, Philip J.; Rossen, Kai; Dormer, Peter G.; Reamer, Robert A.; Welch, Christopher J.; Mathre, David J.; Tsou, Nancy N.; McNamara, James M.; Reider, Paul J. Journal of the American Chemical Society, 2003 , vol. 125, # 8 p. 2129 - 2135

104-63-2 563-96-2 ~73% 287930-73-8

文献：Nelson, Todd D.; Rosen, Jonathan D.; Brands, Karel M.J.; Craig, Bridgette; Huffman, Mark A.; McNamara, James M. Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8917 - 8920

109745-70-2 104-63-2 ~14% 287930-73-8

文献：Brands, Karel M. J.; Payack, Joseph F.; Rosen, Jonathan D.; Nelson, Todd D.; Candelario, Alexander; Huffman, Mark A.; Zhao, Matthew M.; Li, Jing; Craig, Bridgette; Song, Zhiguo J.; Tschaen, David M.; Hansen, Karl; Devine, Paul N.; Pye, Philip J.; Rossen, Kai; Dormer, Peter G.; Reamer, Robert A.; Welch, Christopher J.; Mathre, David J.; Tsou, Nancy N.; McNamara, James M.; Reider, Paul J. Journal of the American Chemical Society, 2003 , vol. 125, # 8 p. 2129 - 2135

108228-02-0 104-63-2 ~% 287930-73-8

文献：Nelson, Todd D.; Rosen, Jonathan D.; Brands, Karel M.J.; Craig, Bridgette; Huffman, Mark A.; McNamara, James M. Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8917 - 8920

上下游产品

上游产品  6
110843-90-8 298-12-4 104-63-2 563-96-2
109745-70-2 108228-02-0
下游产品  3
171338-27-5 287930-75-0 170729-80-3

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%