763114-25-6

• 常用中文名：2-氟-5-[(3-氧代-1(3H)-异苯并呋喃亚基)甲基]苯腈
• 常用英文名：2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile
• CAS号：763114-25-6
• 分子式：C₁₆H₈FNO₂
• 分子量：265.239
• 相关类别： 有机原料 有机氟化合物 氟苯腈系列
• 发布时间：2018-12-28 17:31:24
• 更新时间：2026-07-03 12:13:04

名称

• 中文名: 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃亚基)甲基]苯腈
• 英文名: 2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile
• 中文别名: 奥拉帕利中间体; 2-氟-5-(3-氧代-3H-异苯并呋喃-1-亚基甲基)苯腈; 2-氟-5-[[3-氧代异苯并呋喃-1(3H)-亚基]甲基]苯腈; 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃甲叉基苯甲腈; 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃亚基)甲基]苯腈 (奥拉帕尼); 2-氟-5-[(3-氧-1(3H)-异苯并呋喃烯)甲基]-苯甲腈; 2-氟-5-(3-氧代-3H-异苯并呋喃-1-亚基甲基) - 苄腈; 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃亚基)甲基]苯腈(简称奥拉帕尼中间体); 2-氟-5-(3-氧代-3H-异苯并呋喃-1-亚甲基)-苄腈; 奥拉帕尼中间体 顺反混合物; 2-氟-5-(3-氧代-3H-异苯并呋喃-1-基亚甲基)苯腈; 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃甲叉基苯甲腈(中间体Ⅰ); 2-氟-5-(3-氧代-3H-异苯并呋喃-1-亚基甲基)苄氰; 奥拉帕尼杂质76; “2-氟-5-(3-氧代异苯并呋喃-1(3H)-亚乙基)甲基)苯甲腈”; 奥拉帕尼13; 奥拉帕尼24; 奥拉帕尼23; 奧拉帕利杂质 42; 2-氟-5-[(3-氧代-1(3H)-异苯并呋喃亚基)甲基]苯腈(763-6)
• 英文别名: 2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile; 3-(3-cyano-4-fluorobenzylidene)isobenzofuran-1(3H)-one; (Z)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile; (E)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile; 2- Fluoro-5-[(3-oxo-1(3H)-isobenzo-furanylidene)-methyI]I- benzonitrile; 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]benzoni; 2-Fluoro-5-(3-oxo-3H-isobenzofuran-1-ylidenemethyl)-benzonitrile; 2-Fluoro-5- (3-oxo-1 (3H) - isobenzofuran) methyl] benzonitrile; 2-fluoro-5-[(3-oxo-1,3-dihydro-2-benzofuran-1-ylidene)methyl]benzonitrile; 2-Fluoro-5-[(Z)-(3-oxo-2-benzofuran-1(3H)-ylidene)methyl]benzonitrile; 2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzoni; 2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile; 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile; Olapib Impurity 76; 2-fluoro-5-[(E/Z)-(3-oxo-2-benzofuran-1(3H)-ylidene)methyl]benzonitrile; 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)meth; C16H8FNO2 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile 763-6; 2-fluoro-5-(3-oxo-1,3-dihydroisobenzofuranylidene methyl)benzonitrile; 2-fluoro-5-[(Z/E)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile; Benzonitrile, 2-fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 430.1±45.0 °C at 760 mmHg
• 分子式: C₁₆H₈FNO₂
• 分子量: 265.239
• 闪点: 213.9±28.7 °C
• 精确质量: 265.053894
• PSA: 50.09000
• LogP: 3.50
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.648
• 储存条件: 室温，干燥密封

安全

• 海关编码: 2932209090

合成路线

61260-15-9 218301-22-5 ~% 763114-25-6

文献：WO2012/71684 A1, ; Page/Page column 23 ; WO 2012/071684 A1

17858-15-0 218301-22-5 ~% 763114-25-6

文献：WO2008/47082 A2, ; Page/Page column 27 ; WO 2008/047082 A2

119-67-5 ~% 763114-25-6

文献：WO2012/71684 A1, ; WO 2012/071684 A1

77771-02-9 ~% 763114-25-6

文献：WO2012/71684 A1, ; WO 2012/071684 A1

上下游产品

上游产品  5
61260-15-9 218301-22-5 17858-15-0 119-67-5
77771-02-9
下游产品  3
763114-26-7 763111-49-5 763114-04-1

海关

海关编码	2932209090
中文概述	2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%