763114-26-7

• 常用中文名：5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸
• 常用英文名：2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoicacid
• CAS号：763114-26-7
• 分子式：C₁₆H₁₁FN₂O₃
• 分子量：298.268
• 相关类别： 有机原料 有机氟化合物 氟苯甲酸系列
• 发布时间：2018-12-29 09:16:29
• 更新时间：2026-07-11 18:38:37

名称

• 中文名: 5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸
• 英文名: 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
• 中文别名: 5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸(中间体3); 2-氟-5-(4-氧代-3,4-二氢酞嗪-1-甲基)苯甲酸 (奥拉帕尼); 5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸 奥拉帕尼中间体; 2-氟-5-[(4-氧亚基-3,4-二氢酞嗪-1-基)甲基]苯甲酸; 奥拉帕尼杂质1; 2-氟-5-(4-氧代-3,4-二氢邻苯二甲嗪-1-基)甲基)苯甲酸; 2-氟-5-((4-氧代-3,4-二氢二氮杂萘-1-基)甲基)苯甲酸; 2-氟-5-[(4-氧代-3,4-二氢酞嗪-1-基)甲基]苯甲酸; 2-氟-5-(4-氧代-3,4-二氢酞嗪-1-甲; 奥拉帕利酸; 2-氟-5-[(4-氧代-3,4-二氢-1-酞嗪基)甲基]苯甲酸; 5-[(3,4-二氢-4-氧代-1-肽嗪)甲基]-2-氟苯甲酸; 2-氟-5-[(4-氧-3,4-二氢噻嗪-1-基)甲基]苯甲酸; 奥帕里布杂质A; 奥拉帕尼中间体/5-[(3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸; 2-氟-5-(4-氧代-3,4-二氢酞嗪-1-甲基); 2-氟-5 - ((4-氧代-3,4- 二氢酞嗪-1-基)甲基)苯甲酸; 2-氟-5 - ((4-氧代-3,4- DIHYDROPHTHALAZIN-1-基)甲基)苯甲酸; 奥拉帕尼中间体; 5-[(3,4-二氢-4-氧代-1-酞嗉基)甲基]-2氟苯甲酸; 2-氟-5-(4-氧代-3,4-二氢酞嗪-1-甲基)苯甲酸; 赛乐西帕相关杂质; 二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯腈; 奥拉帕利杂质33; (3,4-二氢-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸; 4-[(3-羧基-4-氟苯基)甲基]酞嗪-1(2H)-酮; 奥拉帕尼中间体AL-2; 奥拉帕尼中间体2; 奥拉帕尼15; 5-[(3,4-二氢-4-氧代-1-酞嗪基) 甲基]-2-氟苯甲酸(中间体Ⅱ); 奧拉帕利杂质 2
• 英文别名: Olapib intermediate 763-7; 5- [(3,4-Dihydro-4-oxo-1-phthaloyl) methyl] -2-fluorobenzoic acid; 2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoic acid; 2-Fluoro-5-[(4-oxo-3,4-dihydro-1-phthalazinyl)methyl]benzoic Acid; Olapib Intermediate 1; 2-Fluoro-5-[(4-oxo-3,4-dihydrophthalazin-yl)methyl] benzoic acid; 2-fluoro-5-((4-oxo-3,4- OH dihydrophthalazin-1-yl)Methyl)benzoic acid; Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid; 5-[(3,4-Dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluoro-Benzoic acid; 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoicaci; 2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylm ethyl)benzo; 763-72-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoicacid; Olapali impurity 25; 2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylmethyl)benzoic a; 2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)Methyl]benzoic acid; C16H11FN2O3 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid 763-7; 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid; 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)be; Benzoic acid, 5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluoro; 2-Fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid; 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl); EOS-61877; (2-Fluoro-5-(4-oxo-3,4-dihydrophthalazin-1-ylMethyl)benzoic acid)763-7; 2-Fluoro-5-[(4-oxo-3,4-dihydro-1-phthalazinyl)methyl]benzoic acid; 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)

物化性质

• 密度: 1.42
• 分子式: C₁₆H₁₁FN₂O₃
• 分子量: 298.268
• 精确质量: 298.075378
• PSA: 83.31000
• LogP: 2.13
• 折射率: 1.661
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

763114-25-6 ~% 763114-26-7

文献：WO2012/71684 A1, ; Page/Page column 23-24 ; WO 2012/071684 A1

1021298-68-9 ~% 763114-26-7

文献：WO2008/47082 A2, ; Page/Page column 28 ; WO 2008/047082 A2

96-36-6 119-67-5 ~97% 763114-26-7 61260-15-9

文献：Kudos Pharmaceuticals Limited; Maybridge Limited Patent: US2005/59663 A1, 2005 ; US 20050059663 A1

119-67-5 ~% 763114-26-7

文献：WO2012/71684 A1, ; WO 2012/071684 A1

61260-15-9 ~% 763114-26-7

文献：WO2012/71684 A1, ; WO 2012/071684 A1

218301-22-5 ~% 763114-26-7

文献：WO2012/71684 A1, ; WO 2012/071684 A1

77771-02-9 ~% 763114-26-7

文献：WO2012/71684 A1, ; WO 2012/071684 A1

上下游产品

上游产品  7
763114-25-6 1021298-68-9 96-36-6 119-67-5
61260-15-9 218301-22-5 77771-02-9
下游产品  3
1174043-16-3 763111-49-5 763114-04-1

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%