186611-44-9

• 常用中文名：Angiogenesis Inhibitor
• 常用英文名：Angiogenesis Inhibitor
• CAS号：186611-44-9
• 分子式：C₁₂H₉N₃O
• 分子量：211.22
• 发布时间：2022-05-20 11:08:20
• 更新时间：2024-04-07 13:48:57
• Angiogenesis抑制剂是一种细胞可渗透的吲哚酮化合物，其显示出的抗血管生成特性与SU5416相当。Angiogenesis抑制剂还充当EGFR（hEGF-R酪氨酸激酶）活性的中度ATP竞争性抑制剂。 Angiogenesis Inhibitor is a cell-permeable indolinone compound that displays anti-angiogenesis properties with a potency that is comparable to that of SU5416. Angiogenesis Inhibitor also acts as a moderate ATP-competitive inhibitor of EGFR (hEGF-R tyrosine kinase) activity.

名称

• 英文名: Angiogenesis Inhibitor
• 英文别名: 2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-, (3Z)-; (Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one; 3-(1H-imidazol-4-ylmethylene)-1,3-dihydro-2H-indol-2-one; MFCD05668779; (3Z)-3-(1H-imidazol-5-ylmethylidene)-1,3-dihydro-2H-indol-2-one; (3Z)-3-(1H-Imidazol-5-ylmethylene)-1,3-dihydro-2H-indol-2-one; 3-(1H-imidazol-5-ylmethylidene)-1H-indol-2-one

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 572.7±50.0 °C at 760 mmHg
• 分子式: C₁₂H₉N₃O
• 分子量: 211.22
• 闪点: 300.2±30.1 °C
• 精确质量: 211.074554
• LogP: 1.01
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.737
• 储存条件: 2-8°C储存
• 水溶解性: Soluble in DMSO (5 mg/ml).