| 中文名 | 2,3-二硝基甲苯 |
|---|---|
| 英文名 | 1-methyl-2,3-dinitrobenzene |
| 中文别名 |
1-甲基-2,3-二硝基苯
3-甲基-1,2-二硝基苯 2,3-二氟-4-碘苯甲醛 |
| 英文别名 |
2,3-Dinitrotoluol
Benzene,1-methyl-2,3-dinitro 2,3-DNT 1,3-dinitrotoluene Toluene,2,3-dinitro EINECS 210-013-5 2,3-DINITROTOLUENE MFCD00007178 |
| 密度 | 1.407 g/cm3 |
|---|---|
| 沸点 | 331.5ºC at 760 mmHg |
| 熔点 | 59-61 °C(lit.) |
| 分子式 | C7H6N2O4 |
| 分子量 | 182.13400 |
| 闪点 | 170.2ºC |
| 精确质量 | 182.03300 |
| PSA | 91.64000 |
| LogP | 2.85780 |
| 储存条件 | 本品应密封保存 |
| 稳定性 | 常温常压下稳定 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:0 3.氢键受体数量:4 4.可旋转化学键数量:0 5.互变异构体数量:无 6.拓扑分子极性表面积91.6 7.重原子数量:13 8.表面电荷:0 9.复杂度:220 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状：黄色针状结晶 2. 密度（g/mL,25/4℃）： 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：59-61 5. 沸点（ºC,常压）： 6. 沸点（ºC,5.2kPa）：未确定 7. 折射率：n 20/D 1.428(lit.) 8. 闪点（ºC）：113 9. 比旋光度（º）： 10. 自燃点或引燃温度（ºC）： 11. 蒸气压（kPa,25ºC）： 12. 饱和蒸气压（kPa,60ºC）： 13. 燃烧热（KJ/mol）： 14. 临界温度（ºC）： 15. 临界压力（KPa）： 16. 油水（辛醇/水）分配系数的对数值： 17. 爆炸上限（%,V/V）： 18. 爆炸下限（%,V/V）： 19. 溶解性：不溶于水 |
Synonym:1-Methyl-2,3-Dinitrobenzene Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 23/24/25 45 48/22 62 50/53 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. May cause cancer. Harmful : danger of serious damage to health by prolonged exposure if swallowed. Possible risk of impaired fertility. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: May cause skin irritation. May cause cyanosis of the extremities. Ingestion: May cause irritation of the digestive tract. May cause liver damage. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. Overexposure may cause methemoglobinemia. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. Inhalation can cause systemic acidosis and methemoglobinemia. May cause liver damage. Chronic: Prolonged exposure may cause anemia and methemoglobinemia, characterized by dizziness, drowsiness, headache, breath shortness, cyanosis (bluish skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. May cause cancer according to animal studies. Chronic exposure may cause liver damage. There is a danger of cumulative effects. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Alcoholic beverage consumption may enhance the toxic effects of this substance. For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood. Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits CAS# 602-01-7: CAS# 25321-14-6: United States OSHA: 1.5 mg/m3 TWA Belgium - TWA: 0.15 mg/m3 VLE Malaysia: 0.2 mg/m3 TWA Spain: 0.15 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystals Color: light yellow Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 59.00 - 61.00 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H6N2O4 Molecular Weight: 182.14 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Dust generation, excess heat. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 602-01-7: XT1400000 CAS# 25321-14-6: XT1300000 LD50/LC50: CAS# 602-01-7: Draize test, rabbit, skin: 500 mg/24H Mild; Oral, mouse: LD50 = 1072 mg/kg; Oral, rat: LD50 = 911 mg/kg. CAS# 25321-14-6: Oral, mouse: LD50 = 750 mg/kg. Carcinogenicity: 2,3-Dinitrotoluene - Not listed by ACGIH, IARC, or NTP. Dinitrotoluene (mixed isomers) - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 5/1/96 Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: Fish: Bluegill/Sunfish: 330ug/L; 96H; Static Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA." Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: DINITROTOLUENES Hazard Class: 6.1 UN Number: 2038 Packing Group: II IMO Shipping Name: DINITROTOLUENES Hazard Class: 6.1 UN Number: 2038 Packing Group: II RID/ADR Shipping Name: DINITROTOLUENES Hazard Class: 6.1 UN Number: 2038 Packing group: II USA RQ: CAS# 25321-14-6: 10 lb final RQ; 4.54 kg final RQ Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T N Risk Phrases: R 45 May cause cancer. R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. R 48/22 Harmful : danger of serious damage to health by prolonged exposure if swallowed. R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R 62 Possible risk of impaired fertility. Safety Phrases: S 53 Avoid exposure - obtain special instructions before use. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S 60 This material and its container must be disposed of as hazardous waste. S 61 Avoid release to the environment. Refer to special instructions/safety data sheets. WGK (Water Danger/Protection) CAS# 602-01-7: No information available. CAS# 25321-14-6: No information available. Canada CAS# 602-01-7 is listed on Canada's NDSL List. CAS# 25321-14-6 is listed on Canada's DSL List. CAS# 602-01-7 is not listed on Canada's Ingredient Disclosure List. CAS# 25321-14-6 is listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 602-01-7 is listed on the TSCA inventory. CAS# 25321-14-6 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
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生态学数据: 该物质有毒,对环境可能有危害，应给予特别注意
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
| 符号 |
GHS06, GHS08, GHS09 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H301 + H311 + H331-H341-H350-H361f-H373-H410 |
| 警示性声明 | P201-P261-P273-P280-P301 + P310-P311 |
| 个人防护装备 | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| 危害码 (欧洲) | T: Toxic;N: Dangerous for the environment; |
| 风险声明 (欧洲) | R45 |
| 安全声明 (欧洲) | S53-S45-S60-S61 |
| 危险品运输编码 | UN 3454 6.1/PG 2 |
| WGK德国 | 3 |
| RTECS号 | XT1400000 |
| 包装等级 | II |
| 危险类别 | 6.1(a) |