46193-76-4

• 常用中文名：4H-噻吩[3,2-b]吡咯-5-羧酸乙酯
• 常用英文名：Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate
• CAS号：46193-76-4
• 分子式：C₉H₉NO₂S
• 分子量：195.238
• 发布时间：2019-01-02 20:20:41
• 更新时间：2026-09-27 17:56:53

名称

• 中文名: 4H-噻吩[3,2-b]吡咯-5-羧酸乙酯
• 英文名: Ethyl 4H-Thieno[2,3-d]Pyrrole-5-Carboxylate
• 中文别名: 4H-噻吩[3,2B]吡咯-5-甲酸乙酯; 4H-噻吩并[3,2-B]吡咯-5-羧酸乙酯; 4H-噻吩并[3,2-B]吡咯-5-甲酸乙酯; 4氢-噻吩[3,2-B]吡咯-5-羧酸乙酯
• 英文别名: Ethyl 4H-thieno[2,3-d]pyrrole-5-cboxylate; 4H-Thieno[3,2-b]pyrrole-5-cboxylic acid, ethyl ester; ETHYL 4H-THIENO[3,2-B]PYRROLE-5-CBOXYLATE; 5-(Ethoxycbonyl)-4H-thieno[3,2-b]pyrrole; 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, ethyl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 345.7±22.0 °C at 760 mmHg
• 熔点: 131-132ºC
• 分子式: C₉H₉NO₂S
• 分子量: 195.238
• 闪点: 162.9±22.3 °C
• 精确质量: 195.035400
• PSA: 70.33000
• LogP: 4.03
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.652
• 储存条件: 室温

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

98-03-3 637-81-0 ~50% 46193-76-4

文献：Jiang, Xin-Dong; Zhang, Houjun; Zhang, Yuanlin; Zhao, Weili Tetrahedron, 2012 , vol. 68, # 47 p. 9795 - 9801,7

1056976-66-9 ~66% 46193-76-4

文献：AstraZeneca UK Limited Patent: US6479527 B1, 2002 ; US 6479527 B1

35355-50-1 ~93% 46193-76-4

文献：Wu, Yayang; Cheng, Chi; Jiao, Lijuan; Yu, Changjiang; Wang, Sufan; Wei, Yun; Mu, Xiaolong; Hao, Erhong Organic Letters, 2014 , vol. 16, # 3 p. 748 - 751

98-03-3 ~% 46193-76-4

文献：Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298

64-17-5 39793-31-2 ~% 46193-76-4

文献：GLAXO GROUP LIMITED; BLUNT, Richard; EATHERTON, Andrew John; GARZYA, Vincenzo; HEALY, Mark Patrick; MYATT, James; PORTER, Roderick Alan Patent: WO2011/12622 A1, 2011 ; Location in patent: Page/Page column 103; 104 ; WO 2011/012622 A1

67268-40-0 ~% 46193-76-4

文献：Soth,S. et al. Canadian Journal of Chemistry, 1978 , vol. 56, p. 1429 - 1434

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%