50428-14-3

• 常用中文名：去氢亚硝基硝苯地平
• 常用英文名：Dehydronitroso Nifedipine
• CAS号：50428-14-3
• 分子式：C₁₇H₁₆N₂O₅
• 分子量：328.31900
• 发布时间：2019-02-17 15:52:51
• 更新时间：2026-08-06 14:50:49

名称

• 中文名: 去氢亚硝基硝苯地平
• 英文名: Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate
• 中文别名: 二甲基-2,6-二甲基-4-(2-亚硝基苯基)吡啶-3,5-二羧酸二; 硝苯地平杂质B; 硝苯地平杂质B/A1A; 硝苯地平 杂质 B(脱氢亚硝基硝苯地平); 2,6-二甲基-4-(2-亚硝基苯基)-3,5-吡啶二甲酸二甲酯; 硝苯地平杂质II; 硝苯地平杂质II( 2，6-二甲基-4-（2-亚硝基苯基）-3，5-吡啶二甲酸二甲酯); 脱氢亚硝基硝苯地平; 硝苯地平杂质B(脱氢硝苯地平); 硝苯地平杂质Ⅱ(2,6-二甲基-4-(2; 硝苯地平杂质II( 2,6-二甲基-4-(2-亚硝基苯基)-3,5-吡啶二甲酸二甲酯); 2,6-二甲基-4-(2-亚硝基苯基)吡啶-3,5-二羧酸二甲酯; 硝苯地平杂质Ⅱ(2,6-二甲基-4-(2-亚硝基苯基)-3,5-吡啶二甲酸二甲酯); 二甲基 2,6-二甲基-4-(2-亚硝基苯基)吡啶-3,5-二甲酸酯; 脱氢亚硝苯地平; 硝苯地平脱氢杂质; 硝苯地平杂质; 硝苯地平杂质II(杂质B); 硝苯地平杂质B 标准品
• 英文别名: Dimethyl 2,6-Dimethyl-4-(2-nitrosop; 3,5-Dimethyl Ester_x000b_2,6-Dimethyl-3,5-dicbomethoxy-4-(2-nitrosophenyl)pyridine; Nifedipine impurity B Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5- dicboxylate (nitrophenylpyridine analogue); Azilstan medoxomil impurity307; dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicboxylate (nitrosophenylpyridine analogue); 4-(2-Nitrosophenyl)-2,6-dimethyl-3,5-dimethoxycarbonylpyridine; Nifedipine dehydro nitroso-d6; Nifedipine Impurity B (Nifedipine nitrosophenylpyridine analog); Nifedipine impurity B CRS; NIFEDIPINE IMP B; Nifedipine Impurity B (Dehydronitroso Nifedipine); Nifedipine-2; Dehydronitrosonifedipine; Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicboxylate; 2,6-Ntp; 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicboxylic acid dimethyl ester; dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicboxylate; 2,6-DiMethyl-4-(2-nitrosophenyl)-3,5-pyridinedicboxylic Acid 3,5-DiMethyl Ester 2,6-DiMethyl-3,5-dicboMethoxy-4-(2-nitrosophenyl)pyridine; 2,6-Dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicboxylic Acid; Nifedipine impurity B; Nifedipine Impurity 2; 3,5-Pyridinedicboxylic acid, 2,6-dimethyl-4-(2-nitrosophenyl)-, 3,5-dimethyl ester; Nifedipine Impurity II:Dehydronitroso Nifedipine; 3,5-Dimethyl Ester 2,6-Dimethyl-3,5-dicbomethoxy-4-(2-nitrosophenyl)pyridine; 4-(2-Nitrosophenyl)-2,6-diMethyl-3,5-diMethoxycbonylpyridine; Dimethyl 2,6-Dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicboxylate (Nitrosophenylpyridine Analogue of Nifedipine); dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate; Nifedipine Impurity II; Nifedipine Nitrosophenylpyridine Analog; Dimethyl 4-(2-nitrosophenyl)-2,6-dimethylpyridine-3,5-dicboxylate; Nifidipine Impurity B

物化性质

• 密度: 1.26g/cm3
• 沸点: 449ºC at 760 mmHg
• 分子式: C₁₇H₁₆N₂O₅
• 分子量: 328.31900
• 闪点: 225.3ºC
• 精确质量: 328.10600
• PSA: 94.92000
• LogP: 3.33650
• 折射率: 1.579

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302-H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933399090

合成路线

21731-17-9 ~% 50428-14-3

文献：Goerlitzer; Buss Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949

119777-23-0 ~% 50428-14-3 67035-22-7

文献：Nikolic, Vesna; Ilic, Dusica; Nikolic, Ljubisa; Stankovic, Mihajlo; Cakic, Milorad; Stanojevic, Ljiljana; Kapor, Anges; Popsavin, Mirjana Central European Journal of Chemistry, 2010 , vol. 8, # 4 p. 744 - 749

21829-25-4 ~99% 50428-14-3

文献：Vries, Henk de; Henegouwen, M. J. Beijersbergen van Photochemistry and Photobiology, 1995 , vol. 62, # 6 p. 959 - 963

21829-25-4 ~87% 50428-14-3 142271-31-6

文献：Merillon, J. M.; Liu, D.; Laurent, Y.; Rideau, M.; Viel, C. Phytochemistry (Elsevier), 1992 , vol. 31, # 5 p. 1609 - 1612

552-89-6 ~% 50428-14-3

文献：Goerlitzer; Buss Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949

105-45-3 ~% 50428-14-3

文献：Goerlitzer; Buss Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949

21829-25-4 ~95% 50428-14-3 67035-22-7

文献：Fasani, Elisa; Dondi, Daniele; Ricci, Andrea; Albini, Angelo Photochemistry and Photobiology, 2006 , vol. 82, # 1 p. 225 - 230

上下游产品

上游产品  5
21829-25-4 552-89-6 105-45-3 21731-17-9
119777-23-0
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%