3759-92-0

• 常用中文名：盐酸呋喃它酮
• 常用英文名：Furaltadone (hydrochloride)
• CAS号：3759-92-0
• 分子式：C₁₃H₁₇ClN₄O₆
• 分子量：360.750
• 相关类别： 原料药 抗生素类药物 其它抗生素类药
• 发布时间：2018-08-15 11:49:07
• 更新时间：2024-01-02 08:13:12
• Furaltadone盐酸盐有效抗慢性呼吸道疾病和副伤寒感染, 且对胎儿弧菌具有显著的体外活性。

名称

• 中文名: 盐酸呋喃它酮
• 英文名: Furaltadone hydrochloride
• 中文别名: 甲磺酸溴隐亭.甲黄酸溴麦角环肽; 呋喃他酮盐酸盐; 盐酸呋喃他酮; 5-(吗啉甲基)-3-[[(5-硝基-2-呋喃基)亚甲基]氨基]恶唑啉-2-酮盐酸盐
• 英文别名: 2-Oxazolidinone, 5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-, monohydrochloride; 2-Oxazolidinone, 5- (4-morpholinylmethyl)-3-[[(5-nitro-2-furanyl)methylene]amino]-, monohydrochloride; nf-269; 2-Oxazolidinone, 5-(4-morpholinylmethyl)-3-[[(1E)-(5-nitro-2-furanyl)methylene]amino]-, hydrochloride (1:1); EINECS 223-169-4; Furasol hydrochloride; Nitrofurmethone hydrochloride; 2-Oxazolidinone, 5-(4-morpholinylmethyl)-3-(((5-nitro-2-furanyl)methylene)amino)-, monohydrochloride (9CI); UNII:37Q02H7JT2; Nf-902 hydrochloride; 2-Oxazolidinone, 5- (morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-, monohydrochloride; 5-(4-Morpholinylmethyl)-3-{(E)-[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one hydrochloride (1:1); 5-(morpholin-4-ylmethyl)-3-{[(E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one hydrochloride (1:1); FURALTADONEHCLMONOHYDRATE; MFCD00058201; Furaltadone hydrochloride; 5-(Morpholin-4-ylmethyl)-3-{[(E)-(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one hydrochloride (1:1); Furmethonol hydrochloride; Furaltadone HCl; 5-(Morpholinomethyl)-3-(((5-nitro-2-furyl)methylene)amino)oxazolidine-2-one hydrochloride; Furaltadone (hydrochloride)

物化性质

• 沸点: 461.4ºC at 760 mmHg
• 熔点: >300?C (dec.)
• 分子式: C₁₃H₁₇ClN₄O₆
• 分子量: 360.750
• 闪点: 232.8ºC
• 精确质量: 360.083649
• PSA: 113.33000
• LogP: 1.87570
• 外观性状: 黄色固体
• 蒸汽压: 1.08E-08mmHg at 25°C
• 储存条件: 2-8°C

生物活性

• 描述: Furaltadone盐酸盐有效抗慢性呼吸道疾病和副伤寒感染, 且对胎儿弧菌具有显著的体外活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RQ3630000 CHEMICAL NAME : 2-Oxazolidinone, 5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)- , monohydrochloride CAS REGISTRY NUMBER : 3759-92-0 LAST UPDATED : 199410 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C13-H16-N4-O6.Cl-H MOLECULAR WEIGHT : 360.79 WISWESSER LINE NOTATION : T6N DOTJ A1- ET5NVOTJ ANU1- BT5OJ ENW &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - other changes in urine composition TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 190 mg/kg TOXIC EFFECTS : Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - other changes in urine composition MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 100 umol/L REFERENCE : RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 75,424,1978

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R22
• 危险品运输编码: UN 3249
• WGK德国: 3
• RTECS号: RQ3630000
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2934999090

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%