79-90-3

• 常用中文名：曲比氯铵
• 常用英文名：triclobisonium chloride
• CAS号：79-90-3
• 分子式：C₃₆H₇₄Cl₂N₂
• 分子量：605.89200
• 相关类别： 天然产物 黄酮类化合物
• 发布时间：2018-06-18 18:48:21
• 更新时间：2024-01-02 21:03:58

名称

• 中文名: 曲比氯铵
• 英文名: 6-[dimethyl-[4-(2,2,6-trimethylcyclohexyl)butan-2-yl]azaniumyl]hexyl-dimethyl-[4-(2,2,6-trimethylcyclohexyl)butan-2-yl]azanium,dichloride
• 英文别名: Ro-5-0810/1; Hexamethylenebis(dimethyl(1-methyl-3-(2,2,6-trimethylcyclohexyl)propyl)ammonium chloride); EINECS 201-232-7; Chlorure de triclobisonium [INN-French]; Triclobisonii chloridum [INN-Latin]; Triclobisonium chloride; Triburon chloride; Triburon; Chloruro de triclobisonio [INN-Spanish]; 1,6-bis[1-methyl-3-(2,2,6-trimethylcyclohexyl)-propyldimethyl ammonium chloride]-hexane; N,N,N',N'-Tetramethyl-N,N'-bis-<1-methyl-3-(2,2,6-trimethyl-cyclohexyl)-propyl>-hexan-1,6-diammonium; Hexamethylenebis(dimethyl(1-methyl-3-(2,2,6-trimethylcyclohexyl)propyl)ammonium) dichloride

物化性质

• 分子式: C₃₆H₇₄Cl₂N₂
• 分子量: 605.89200
• 精确质量: 604.52300
• LogP: 3.96980

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BQ8343000 CHEMICAL NAME : Ammonium, hexamethylenebis(1-methyl-3-(2,2,6-trimethylcyclohexy l)propyl)bis(dimethyl -, dichloride CAS REGISTRY NUMBER : 79-90-3 LAST UPDATED : 199203 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C36-H74-N2.2Cl MOLECULAR WEIGHT : 606.02 WISWESSER LINE NOTATION : L6TJ A1 A1 C1 B2Y1&K1&1&6K1&1&Y1&2- BL6TJ A1 A1 C1 &G 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 375 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 154 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,780,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >20 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 8 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 9,267,1959

安全

• 风险声明 (欧洲): 36/37/38
• 危险品运输编码: UN 3264 8/PG 3
• WGK德国: 3

合成路线

629-09-4 34714-42-6 ~% 79-90-3

文献：Teitel,S. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 780 - 787

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