881-95-8

• 常用中文名：DL-3-甲氧基肾上腺素盐酸盐
• 常用英文名：METANEPHRINEHYDROCHLORIDE
• CAS号：881-95-8
• 分子式：C₁₀H₁₆ClNO₃
• 分子量：233.692
• 发布时间：2018-08-28 15:39:09
• 更新时间：2026-07-02 10:21:05
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名称

• 中文名: (+/-)-变肾上腺素盐酸盐
• 英文名: 4-(1-Hydroxy-2-(methylamino)ethyl)-2-methoxyphenol hydrochloride
• 中文别名: 甲氧基肾上腺素; (+/-)-甲基肾上腺素盐酸盐; )-变肾上腺素盐酸盐; DL-M-O-甲基肾上腺素盐酸盐; 变肾上腺素盐酸盐; 甲醇中DL-变肾上腺素盐酸盐溶液; D,L-盐酸METANHRINE盐; 甲醇中D.L-变肾上腺素盐酸盐; DL-变肾上腺素盐酸盐标准品; 盐酸间肾上腺素; 盐酸间肾碱; 苯并苯甲醇,4-羟基-3-甲氧基-Α-[(甲基氨基)甲基]-,盐酸盐(1:1); 盐酸变肾上腺素; 4-(1-羟基-2-(甲基氨基)乙基)-2-甲氧基苯酚盐酸盐; 间甲肾上腺素盐酸盐
• 英文别名: Methoxyadrenaline; DL-MetanhrineCl (not deuterated); (+-)-4-hydroxy-3-methoxy-alpha-((methylamino)methyl)benzenemethanolhydrochlo; rac Metanhrine Hydrochloride Salt/Metanhrine HCl; D,L-Metanhrine hydrochloride salt; DL-METANHRINE HYDROCHLORIDE; 3-methoxy-adrenalinhydrochloride; 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxy-phenol hydrochloride; DL-3-O-Methyladrenaline hydrochloride; Metanhrine HCl (solution); alpha-((methylamino)methyl)-vanillylalcohohydrochloride; (+/-)-Metanhrine hydrochloride in methanol; Metanhrine 13C D3 hydrochloride; rac Metanhrine Hydrochloride Salt(as free base) in Methanol; rac Metanhrine Hydrochloride Salt (0.1mg/mL in Methanol); α-[(MethylaMino)Methyl]-vanillyl Alcohol Hydrochloride; 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride; METANHRINE HYDROCHLORIDE; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride (1:1); Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]-, (αR)-, hydrochloride (1:1); 4-HYDROXY-3-METHOXY-ALPHA-[METHYLAMINOMETHYL]BENZENE-METHANOL HYDROCHLORIDE; (+/-)-alpha-[(Methylamino)methyl]vanillyl alcohol hydrochloride; Metadrenaline Hydrochloride; DL-M-O-METHYLINHRINE HYDROCHLORIDE; (+/-)-Metanhrine hydrochloride; DL-m-O-Methylinhrine hydrochloride, 4-Hydroxy-3-methoxy-α-(methylaminomethyl)benzene-methanol hydrochloride; DL-M-O-Methylinhrine hydrochlorideNew; METANHRINE (HCL); (±)-Metanhrine hydrochloride solution; Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]- , hydrochloride (1:1) (ACI); inhrine Impurity 29; 4-HYDROXY-3-METHOXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE; (.+-)-alpha-[(methylamino)methyl]vanillyl alcohol hydrochloride; Metanhrine Hydrochloride (Rac); m-O-Methyladrenaline hydrochloride; Adrenaline Impurity 77; 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-benzenemethanohydrochlorid; Metanhrine hydrochloride salt; 4-Hydroxy-3-Methoxy-α-[(MethylaMino)Methyl]benzeneMethanol Hydrochloride; DL-MetanhrineHCl; METANHRINE HYDROCHLORIDE REFERENC E STD. FOR CH; dl-m-o-methylepinephrine hydrochloride; rac Metanhrine hydrochloride

物化性质

• 沸点: 378.8ºC at 760 mmHg
• 熔点: 180-182ºC
• 分子式: C₁₀H₁₆ClNO₃
• 分子量: 233.692
• 闪点: 182.9ºC
• 精确质量: 233.081863
• PSA: 61.72000
• LogP: 1.84650
• 储存条件: -20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DA4798000 CHEMICAL NAME : Benzenemethanol, 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)- CAS REGISTRY NUMBER : 881-95-8 LAST UPDATED : 199412 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H15-N-O3.Cl-H MOLECULAR WEIGHT : 233.72 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 840 mg/kg/42D-I TOXIC EFFECTS : Cardiac - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - lipids including transport REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,315,1973

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2922509090

合成路线

91012-60-1 ~69% 881-95-8

文献：Kulikov, S. V.; Samartsev, M. A. Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 2 p. 348 - 358

54771-60-7 ~% 881-95-8

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, , vol. 28, # 2 p. 348 - 358

32025-66-4 ~% 881-95-8

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 2.2 p. 280 - 288 Zhurnal Organicheskoi Khimii, , vol. 28, # 2 p. 348 - 358

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%