386750-22-7

• 常用中文名：琥珀酸去甲文拉法辛
• 常用英文名：Desvenlafaxine succinate
• CAS号：386750-22-7
• 分子式：C₂₀H₃₃NO₇
• 分子量：399.48
• 相关类别： 生物化工 抑制剂 神经信号通路(Neuronal Signaling) 5-HT Receptor 调节剂
• 发布时间：2018-07-06 11:32:07
• 更新时间：2026-07-24 09:16:54
• Desvenlafaxine琥珀酸水合物5-羟色胺去甲肾上腺素再摄取抑制剂(SNRI类抗抑郁化合物)。

名称

• 中文名: 琥珀酸去甲文拉法辛
• 英文名: [2-(1-hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium 3-carboxypropanoate monohydrate
• 中文别名: RAC-O-去甲基文拉法辛-D6 琥珀酸盐水合物; 琥珀酸文拉法辛; 甲硫二苯马尼; [2H6] -RAC-O-去甲文拉法辛琥珀酸盐水合物; (±)O-去甲文拉法辛-[D6]琥珀酸盐水合物/精确称量; 琥珀酸去甲基文拉法辛; 4-(2-(二甲基氨基)-1-(1-羟基环己基)乙基)苯酚琥珀酸盐一水物; 琥珀酸地文拉法辛一水合物; Desvenlafaxine Succinate 琥珀酸去甲文拉法辛(甲硫二苯马尼); PH校准液3; 琥珀酸地文拉法辛; 化合物:Desvenlafaxine Succinate; 去甲拉法辛琥珀酸盐; 去甲文拉法辛琥珀酸盐; 琥珀酸去甲文拉法辛,10 MM DMSO 溶液; (±)O-去甲文拉法辛-[D6]琥珀酸盐水合物; 琥珀酸去甲文拉法辛 Desvenlafaxine succinate hydrate; 去甲文拉法辛琥珀酸一水合物; 化合物：Desvenlafaxine Succinate; 珀酸去甲文拉法
• 英文别名: C16H25NO2.HOOCCH2CH2COOH.H2O; Norvenlafaxine succinate; Succinic acid - 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol (1:1); 1-[2-(dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol succinate hydrate; TIANFUCHEM- Desvenlafaxine succinate; Desvenlafaxine succinate monohydrate; (1R)-2-(2-(diMethylaMino)-1-phenylethyl)cyclohexanol; O-Desmethylvenlafaxine succinate hydrate; Desvenlafaxine succinate //BP; 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate monohydrate; Desvenla succinate; Desvenlafaxine (O-DesMethyl Venlafaxine) Succinate Monohydrate; UNII:H9E1T0BI90; ODV succinate hydrate; Desvenlafaxine succinateQ: What is Desvenlafaxine succinate Q: What is the CAS Number of Desvenlafaxine succinate Q: What is the storage condition of Desvenlafaxine succinate Q: What e the applications of Desvenlafaxine succinate; Desvenlafaxine Succinate Monohydrate (O-Desmethylvenlafaxine Succinate Monohydrate); Pristiq succinate hydrate; Desvenlafaxine Succinate (1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol hydrogen butanedioate monohydrate); Desvenlafaxine succinic acid monohydrate; Desvenlafaxine succinate anhydrous; RAC-O-DESMETHYL VENLAFAXINE-D6 SUCCINATE HYDRATE; 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenolsuccinate; Pristiq; Desvenlafaxine (succinate hydrate); [2H6]-rac-O-Desmethyl Venlafaxine Succinate Hydrate; O-desmethyl venlafaxine succinate hydrate; WY 45233 succinate; 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate hydrate; Desvenlafaxine succinate hydrate, 10 mM in DMSO; Phenol, 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-, butanedioate (1:1) (salt); 2-(1-Hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium3-cboxypropanoatemonohydrate; Unii-zb22enf0xr; Butanedioic acid, compd. with 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, hydrate (1:1:1); PRISTIQ SUCCINATE HYDRATE;O-DESMETHYLVENLAFAXINE SUCCINATE HYDRATE

物化性质

• 沸点: 403.8ºC at 760 mmHg
• 分子式: C₂₀H₃₃NO₇
• 分子量: 399.48
• 闪点: 193.2ºC
• PSA: 118.30000
• LogP: 2.66840
• 外观性状: 白色结晶粉末
• 储存条件: Store at +4°C

生物活性

• 描述: Desvenlafaxine琥珀酸水合物5-羟色胺去甲肾上腺素再摄取抑制剂(SNRI类抗抑郁化合物)。
• 相关类别:
  信号通路 >> 神经信号通路 >> 5-羟色胺转运蛋白
  研究领域 >> 神经疾病

合成路线

448904-47-0 ~% 386750-22-7

文献：US2008/188567 A1, ; Page/Page column 9 ;

110-15-6 93413-62-8 ~% 386750-22-7

文献：WO2008/17886 A1, ; Page/Page column 10 ;

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