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118289-55-7

118289-55-7结构式
118289-55-7结构式

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中文名 6-氯-5-(2-氯乙基)羟吲哚
英文名 5-Chloroethyl-6-Chloro-1,3-Dihydro-2H-Indole-2-One
中文别名 5-(2-氯乙基)-6-氯-1,3-二氢-吲哚-2-(2H)-酮
6-氯-5-(2-氯乙氧基)-2-吲哚二酮
5-(2-氯乙基)-6-氯-1,3-二氢-2H-吲哚-2-酮
英文别名 2H-Indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro-
T56 BMV DHJ G2G HG
MFCD03411598
6-Chloro-5-(2-chloroethyl)-2-indolinone
6-Chloro-5-(2-chloroethyl)oxindole
6-Chloro-5-(2-chloroethyl)indolin-2-one
5-Chloroethyl-6-chloro-1,3-dihydro-2H-indole-2-one
6-Chloro-5-(2-chloroethyl)-1,3-dihydro-2H-indol-2-one
EINECS 421-320-0
密度 1.4±0.1 g/cm3
沸点 393.8±42.0 °C at 760 mmHg
熔点 218-221ºC
分子式 C10H9Cl2NO
分子量 230.091
闪点 192.0±27.9 °C
精确质量 229.006119
PSA 29.10000
LogP 2.82
外观性状 固体;White to Yellow to Orange powder to crystal
蒸汽压 0.0±0.9 mmHg at 25°C
折射率 1.592
储存条件 Refrigerator
水溶解性 可溶于:二甲基甲酰胺
6-Chloro-5-(2-chloroethyl)oxindole
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:6-Chloro-5-(2-chloroethyl)oxindole

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
Category 1
Acute aquatic hazard
Long-term aquatic hazardCategory 1
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal wordWarning
Hazard statements
Very toxic to aquatic life
Very toxic to aquatic life with long lasting effects
Precautionary statements:
[Prevention]Avoid release to the environment.
Collect spillage.
[Response]
[Disposal]Dispose of contents/container through a waste management company authorized by
the local government.

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:6-Chloro-5-(2-chloroethyl)oxindole
Percent:>98.0%(GC)
CAS Number:118289-55-7
Synonyms:6-Chloro-5-(2-chloroethyl)-2-indolinone
Chemical Formula:C10H9Cl2NO

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
6-Chloro-5-(2-chloroethyl)oxindole

Section4. FIRST AID MEASURES
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Dry chemical, foam, water spray, carbon dioxide.
Suitable extinguishing
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical:generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Be careful not to let it flow into rivers, etc., since adverse effects on the environment
are concerned.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a refrigerator.
Store away from incompatible materials such as oxidizing agents.
Heat-sensitive
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls:Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Safety glasses. A face-shield, if the situation requires.
Eye protection:
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Crystal- Powder
Form:
Colour:Very pale yellow - Pale reddish yellow
No data available
Odour:
6-Chloro-5-(2-chloroethyl)oxindole

Section9. PHYSICAL AND CHEMICAL PROPERTIES
pH: No data available
Melting point/freezing point:225°C
Boiling point/range:No data available
Flash point:No data available
Flammability or explosive
limits:
Lower:No data available
Upper:No data available
Relative density:No data available
Solubility(ies):
[Water]No data available
[Other solvents]
Soluble:Dimethylformamide(DMF)

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
products:

Section11. TOXICOLOGICAL INFORMATION
Acute Toxicity:No data available
Skin corrosion/irritation: No data available
Serious eyeNo data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
Reproductive toxicity:No data available

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
No data available
Algae:
Persistence / degradability: No data available
No data available
Bioaccumulative
potential(BCF):
Mobility in soil
Log Pow:No data available
Soil adsorption (Koc):No data available
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:9: Miscellaneous dangerous goods.
UN-No:3077
Proper shipping name:Environmentally hazardous substance, solid, n.o.s.
6-Chloro-5-(2-chloroethyl)oxindole

Section14. TRANSPORT INFORMATION
Packing group:III
Marine pollutantY

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A
危害码 (欧洲) N: Dangerous for the environment;
风险声明 (欧洲) R50/53
安全声明 (欧洲) 60-61
海关编码 2933790090

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文献:Journal of Medicinal Chemistry, , vol. 39, # 1 p. 143 - 148

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文献:US2006/89502 A1, ; Page/Page column 7 ;

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文献:Journal of Medicinal Chemistry, , vol. 39, # 1 p. 143 - 148

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文献:Organic Process Research and Development, , vol. 7, # 3 p. 309 - 312

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文献:Organic Process Research and Development, , vol. 7, # 3 p. 309 - 312

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文献:WO2012/20424 A1, ;

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文献:Organic Process Research and Development, , vol. 12, # 6 p. 1142 - 1145
海关编码 2933790090
中文概述 2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%