150728-12-4

• 常用中文名：5-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮
• 常用英文名：5-(2-Methoxyphenoxy)-[2,2'-bipyrimidine]-4,6[1H,5H]-dione
• CAS号：150728-12-4
• 分子式：C₁₅H₁₂N₄O₄
• 分子量：312.280
• 发布时间：2018-12-03 12:02:40
• 更新时间：2026-08-15 11:28:33

名称

• 中文名: 5-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮
• 英文名: 5-(2-Methoxyphenoxy)-[2,2-Bipyrimidine]-4,6(1H,5H)-Dione
• 中文别名: 波生坦二酮; 波生坦杂质8; 5-(2-甲氧基苯氧基)-[2,2'-二; 5-(2-甲氧基苯氧基)-[2,2’-二嘧啶]-4,6(1H,5H)-二酮; 波森坦杂质13; 5-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮(波生坦中间体); 5-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮(SM1)
• 英文别名: (RS)-5-(2-methoxy-phenoxy)-1H-bipyrimidine-4,6-dione; Bosentan Impurity 13; Bosenta dione; 5-(2-methoxyphenoxy)-[2,2'; 5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1h,5h)-dione; 5-(2-METHOXYPHENOXY)-2-(PYRIMIDIN-2-YL)PYRIMIDINE-4,6(1H,5H)-DIONE,PURITY: MIN(HPLC); 2,2'-Bipyrimidine]-4,6(1H,5H)-dione, 5-(2-methoxyphenoxy); 5-(2-Methoxyphenxoy)-[2,2'-bipyrimidine]-4; 5-(2-Methoxyphenxoy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione; 5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidine-4,6(1H,5H)-dione; Bosentan interMediate; 5- (2-Methoxyphenoxy) - [2,2 '- pyrimidine] -4,6 (1H, 5H) - dione; 5-(2-Methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione; 5-(2-Methoxyphenoxy)-[2,2'-BipyriMidine]-4,6(1H,5H); 5-(2-Methoxyphenoxy)-2-(pyriMidin-2-yl)-1,4,5,6-tetrahydropyriMidine-4,6-dione; 5- (2-Methoxyphenoxy) - [2,2 '- Dipyrimidine] -4,6 (1H, 5H) - dione; 5-(O-methoxyphenoxy)-2-pymidin-2-yl)-4,6-(1H,5H)-pymidine dione; 5-(2-Methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione CAS NO.150-4 CAS NO.150-4; 5-(2-Methoxyphenoxy)-2,2'-bipyrimidine-4,6(1H,5H)-dione

物化性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₁₅H₁₂N₄O₄
• 分子量: 312.280
• 精确质量: 312.085846
• PSA: 102.77000
• LogP: -0.24
• 折射率: 1.676
• 储存条件: 2-8°C， 干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

14080-23-0 150726-89-9 ~% 150728-12-4

文献：US2012/136015 A1, ; Page/Page column 6-7 ;

20730-58-9 16879-48-4 ~25% 150728-12-4

文献：AUSPEX PHARMACEUTICALS, INC. Patent: US2008/242687 A1, 2008 ; Location in patent: Page/Page column 32; 34 ; US 20080242687 A1

上下游产品

上游产品  4
14080-23-0 150726-89-9 20730-58-9 16879-48-4
下游产品  1
150728-13-5

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%