150728-13-5

• 常用中文名：4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-二嘧啶
• 常用英文名：4,6-Dichloro-5-(2-methoxyphenoxy)-2,2-bipyrimidine
• CAS号：150728-13-5
• 分子式：C₁₅H₁₀Cl₂N₄O₂
• 分子量：349.172
• 发布时间：2018-12-05 13:20:54
• 更新时间：2026-07-03 09:22:26

名称

• 中文名: 波生坦中间体(I)
• 英文名: 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine
• 中文别名: 波生坦中间体(I)4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-二嘧啶; 波生坦相关物质D 标准品; 伯森坦杂质4; 4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-联嘧啶; 4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-双嘧啶; 波生坦二氯; 2'-BI嘧啶; 波生坦中间体1; 波生坦中间体; 波森坦RC D; 波生坦有关物质1; 4,6-DICHLORO-5-(2-METHOXYPHENOXY)-2,2'-BIPYRIMIDINE4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-二嘧啶; 波生坦相关化合物D; 波生坦相关化合物D:4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-联嘧啶; 2'-双嘧啶; 2'-联嘧啶; 4,6-二氯-5-(2-甲氧基苯氧基)-2,2-二嘧啶; 4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-BI嘧啶; 6-二氯-5-(2-甲氧基苯氧基)-2; 波生坦杂质D; 波生坦相关物质D; 波生坦杂质11(波生坦相关杂质D); 波生坦相关化合物1
• 英文别名: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine >; 4,6-Dichloro-5- (2-methoxyphenyloxy) -2,2 '- Dipyrimidine; 4,6-dichloro-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidine; 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Manufacturer/High quality/Best price/In stock; 4,6-Dichloro-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan interMediate (I); Bosentan RC D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl; Bosentan Impurity 11(Bosentan Related Compound D); 2-(5-(2-methoxyphenoxy)-4,6-dichloropyrimidin-2-yl)pyrimidine; Bosentan Related CoMpound D; 4,6-dichloro-5-(methoxyphenoxy)-2,2'-bipyrimidine; 4,6-Dichloro-5-(O-Methoxyphenoxy)-2-(2-Pyrimidinyl)Pyrimidine; 2,2'-Bipyrimidine, 4,6-dichloro-5-(2-methoxyphenoxy)- (bosentan intermediate); 4,6-dichloro-5-(2-Methoxyphenoxy)-2-(pyriMidin-2-yl)pyriMidine; 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2’-bipyrimidine; Bosentan Related Compound D (4,6-dichloro-5-(2-methoxyphenoxy)-2,2''-bipyrimidine); 2,2'-Bipyrimidine, 4,6-dichloro-5-(2-methoxyphenoxy); 2-(4,6-dichloro-5-(2-methoxyphenoxy) pyrimidin-2-yl)pyrimidine; Bosentan Related Compound D: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; 4,6-Dich; Bosentan Related Compound 1; 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine (bosentan intermediate); 2,2'-Bipyrimidine,4,6-dichloro-5-(2-methoxyphenox; Bosentan Related Compound D (4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine); 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; (4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine)Q: What is (4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine) Q: What is the CAS Number of (4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine) Q: What is the storage condition of (4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine) Q: What e the applications of (4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2-Bipyrimidine); Bosentan Related Compound D (15 mg) (4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine); Intermediate of Bosentan (I); BOSENTAN INTERMEDIATES

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 520.7±60.0 °C at 760 mmHg
• 熔点: 159 °C
• 分子式: C₁₅H₁₀Cl₂N₄O₂
• 分子量: 349.172
• 闪点: 268.7±32.9 °C
• 精确质量: 348.018066
• PSA: 70.02000
• LogP: 1.48
• 外观性状: 棕色固体
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.617
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi: Irritant;
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933599090

合成路线

150728-12-4 ~90% 150728-13-5

文献：US2012/136015 A1, ; Page/Page column 7 ;

329923-15-1 ~97% 150728-13-5

文献：WO2013/57545 A1, ; Paragraph 14-15 ;

329923-17-3 ~% 150728-13-5

文献：WO2011/24056 A2, ; Page/Page column 20 ;

20730-58-9 ~% 150728-13-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 5 p. 955 - 959

150726-89-9 ~% 150728-13-5

文献：WO2011/24056 A2, ;

14080-23-0 ~% 150728-13-5

文献：WO2011/24056 A2, ;

90-05-1 ~% 150728-13-5

文献：WO2011/24056 A2, ;

上下游产品

上游产品  7
150728-12-4 329923-15-1 329923-17-3 20730-58-9
150726-89-9 14080-23-0 90-05-1
下游产品  1
150727-06-3

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%