160844-75-7

• 常用中文名：2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯
• 常用英文名：Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
• CAS号：160844-75-7
• 分子式：C₁₈H₂₀N₂O₃S
• 分子量：344.428
• 发布时间：2018-12-25 08:53:00
• 更新时间：2026-07-01 12:14:59

名称

• 中文名: 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯
• 英文名: Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
• 中文别名: 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯(非布索坦/非布司他中间体); 2-(3-氰基-4-异丁氧基-苯基)-4-甲基-噻唑-5-羧酸乙酯; 2-(3-氰基-4-异丁氧基苯基)-4-甲基-5-噻唑羧酸酯; 2-[3-氰基-4-异丁氧基苯基]-4-甲基噻唑-5-甲酸乙酯; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯 *非布中间体4; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯 (非布索坦中间体4); 非布司他/非布索坦杂质13; 非布司他中间体6; 非布索坦中间体4; 非布司他中间体4; 非布索坦杂质G; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻吩-5-甲酸乙酯; 非布索坦中间体5; 2-(3-氰基-4-异丁氧基苯基)-4-甲基 噻唑-5-甲酸乙酢; 2-(3-氰基-4-异丁氧基苯基-4-甲基嚷哗-5-甲酸乙酯; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯,非布索坦中间体5; 非布司他 中间体 (N-1); 非布司他13; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯噻唑-5-甲酸乙酯; 非布索坦中间体F5; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯(非布索坦中间体); 非布索坦中间体-III; 2-(3-氰基-4-异丁氧苯基)-4-甲基-5-噻唑羧酸乙酯; 非布索坦杂质13; 非不司他杂质23; 非布索坦中间体; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯(非布司他中间体5); 非布索坦乙酯; 2-[3-氰基-4-异丁氧基苯基]-4-甲基噻唑-5-甲酸乙酯(非布司他中间体6); 非布司他中间体,2-(3-氰基-4-异丁氧基苯基)-4-甲基噻 唑-5-甲酸乙酯; 非布司他杂质3; 非不司他杂质3; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸乙酯(非布中五); 2-[3-氰基-4-(2-甲基丙氧基)苯基]-4-甲基噻唑-5-甲酸乙酯; 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑 -5-甲酸乙酯 (F5)"
• 英文别名: Febuxostat Impurity 13; Febuxostat-7; Febuxostat Ethyl Ester Impurity; Ethyl 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecboxylate; Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate; Ethyl 2-(3- cyano -4- isobutyloxyphenyl) -4- methylthiazole -5- cboxylate; 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecboxylate; 2-(4-isobutoxyphenyl)-3-cboxylate)4-methyl-1,3- thiazole-5- cboxylate acid( Febuxostat dicboxylic acid impurity); Febuxostat Ethyl Ester: Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecboxylate; 5-cboxylato-2-[3-cyano-4-(2-Methylpropoxy)phenyl]-1-ethyl-4-Methyl-1H-1; ETHYL 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]- 4-METHYLTHIAZOLE-5-CBOXYLATE; Febuxostat Ethyl Ester (2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecboxylic Acid Ethyl Ester); 5-Thiazolecboxylicacid, 2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-, ethyl ester; 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecboxylic Acid Ethyl Ester; 2-(4-ISOBUTOXYPHENYL)-3-CBOXYLATE)4-METHYL-1,3- THIAZOLE-5; Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazol; ethyl 2-(3-cyano-4-isobutoxyphenyl); 2-(3-Cyano-4-isobutoxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester; ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl; Ethyl> 2-(3-cyano-4-isobutoxyphenyl)-4-Methyl-5-th; 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-cboxylate; Febuxostat Ethyl Ester (2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecboxylic Acid Et; Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecboxylate; 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazol-5-cboxylic acid ethyl esterQ: What is 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazol-5-cboxylic acid ethyl ester Q: What is the CAS Number of 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazol-5-cboxylic acid ethyl ester Q: What is the storage condition of 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazol-5-cboxylic acid ethyl ester; Febuxostat Ethyl Ester; Non-Bust Impurity 23; Febuxostat intermediates，Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4- methyl-5-thiazolecboxylate; Ethyl 2-(3-cyno-4-isobutoxyphenyl)-4-methyl-5- thiazolecboxylate; 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester; 2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Me; l^{4},3-thiazol-1-yl; ethyl ester of febuxostat; 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]-4-METHYL-5-THIAZOLECBOXYLIC ACID ETHYL; Febuxostat Impurity 15/Febuxostat Ethyl Ester/Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-cboxylate; 2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-Thiazolecboxylic acid ethyl ester; 2[3-Cyano-4-(2-methyl propoxy)phenyl]4-methyl-5-thiazole cboxylic acid ethyl ester T); Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecbo; Febuxostat Impurities3; Febuxostat Ethyl Ester Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5- cboxylate; FEBUXOSTAT INT N-1

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 497.1±55.0 °C at 760 mmHg
• 熔点: 176 °C
• 分子式: C₁₈H₂₀N₂O₃S
• 分子量: 344.428
• 闪点: 254.5±31.5 °C
• 精确质量: 344.119476
• PSA: 100.45000
• LogP: 5.70
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.570
• 储存条件: 室温

安全

• 海关编码: 2942000000

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海关

海关编码	2934100090
中文概述	2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%