4033-27-6

• 常用中文名：二氢叶酸
• 常用英文名：Dihydrofolic acid
• CAS号：4033-27-6
• 分子式：C₁₉H₂₁N₇O₆
• 分子量：443.41300
• 相关类别： 研究领域 其他
• 发布时间：2018-10-01 15:27:18
• 更新时间：2026-07-12 19:00:45
• Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。

名称

• 中文名: 二氢叶酸
• 英文名: dihydrofolic acid
• 中文别名: 叶酸相关杂质; 左旋亚叶酸钙杂质7(左旋亚叶酸钙杂质G); 左亚叶酸钙杂质G; 左亚叶酸杂质G盐酸盐; 左叶酸酸钙杂质G; 二氢叶酸 (-20°C); 亚叶酸杂质G; 杂质G(盐酸盐); 7,8-二氢叶酸[干冰运输; (S)-2-(4-(((2-氨基-4-氧代-3,4,7,8-四氢蝶呤-6-基)甲基)氨基)苯甲酰氨基)戊二酸; 左旋亚叶酸钙杂质G; 亚叶酸杂质G(7,8-二氢叶酸); 二氢叶酸 DHF; 亚叶酸钙杂质G; 左旋芳酸钙杂质G
• 英文别名: 7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2; (S)-2-(4-(((2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)Methyl)amino)benzaMido)pentanedioic acid; (S)-2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid; Impurity G of Calcium Levofolinate; FAH2; L-Glutamic acid, N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]; (4-(((2-Imino-4-Oxo-1,2,3,4,7,8-Hexahydropteridin-6-Yl)Methyl)Amino)Benzoyl)-L-Glutamicacid; Folic acid impurity 2/Folinic Acid Impurity G/Dihydrofolic acid/7,8-Dihydrofolic Acid; DIHYDROFOLIC ACID; 7,8-Dihydropteroyl-L-glutamic acid Dihydropteroyl-L-glutamic acid; DIHYDROPTEROYL-L-GLUTAMIC ACID; Folinic Acid Impurity G (7,8-Dihydrofolic Acid); Calcium levoflonate impurity G; (4-(((2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid; Folic Acid 7,8-Dihydro Impurity; 7,8-DIHYDROPTEROYL-L-GLUTAMIC ACID; dihydrofolate; 2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid; Folinic Acid Impurity G; Levofolinate Impurity G; 2-[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid; FolinicAcidImpurityGHCl; N-[4-[[[(2-Amino-1,4,5,6-tetrahydro-4-oxopteridin)-6-yl]methyl]amino]benzoyl]-L-glutamic acid; Dihydrofolic acid 7,8-Dihydropteroyl-L-glutaMic acid; Impurity G (hydrochloride); 7,8-Dihydrofolic acid (DHF); N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)Methyl]amino]benzoyl]-L-GlutaMic acid

物化性质

• 密度: 1.69g/cm3
• 分子式: C₁₉H₂₁N₇O₆
• 分子量: 443.41300
• 精确质量: 443.15500
• PSA: 211.89000
• LogP: 0.62870
• 折射率: 1.762
• 储存条件: -20°C

生物活性

• 描述: Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。
• 相关类别:
  研究领域 >> 其他
  天然产物 >> 其他
• 靶点:

  Human Endogenous Metabolite

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36
• 危险品运输编码: NONH for all modes of transport

合成路线

59-30-3 ~82% 4033-27-6

文献：Khilifa; Ganguly; Bieri; Viscontini Helvetica Chimica Acta, 1980 , vol. 63, # 8 p. 2554 - 2558

142811-49-2 ~% 4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

142811-46-9 ~% 4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

142811-47-0 ~% 4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

142811-48-1 ~% 4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

142811-50-5 ~% 4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

4271-30-1 ~% 4033-27-6

文献：Shiota; Disraely Biochimica et Biophysica Acta, 1961 , vol. 52, p. 467,468 Full Text Show Details Shiota Archives of Biochemistry, 1959 , vol. 80, p. 155,156

142811-51-6 ~% 135-16-0 142811-42-5 31690-11-6 详细

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

上下游产品

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