Dihydrofolic acid structure
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Common Name | Dihydrofolic acid | ||
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CAS Number | 4033-27-6 | Molecular Weight | 443.41300 | |
Density | 1.69g/cm3 | Boiling Point | N/A | |
Molecular Formula | C19H21N7O6 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Dihydrofolic acidDihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. |
Name | dihydrofolic acid |
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Synonym | More Synonyms |
Description | Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
Density | 1.69g/cm3 |
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Molecular Formula | C19H21N7O6 |
Molecular Weight | 443.41300 |
Exact Mass | 443.15500 |
PSA | 211.89000 |
LogP | 0.62870 |
Index of Refraction | 1.762 |
Storage condition | -20°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | 36/37/38 |
Safety Phrases | 26-36 |
RIDADR | NONH for all modes of transport |
Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.
Mol. Pharm. 11(8) , 2631-9, (2014) The antifolate drug methotrexate (MTX) can serve as a dual-functional ligand in antitumoral drug delivery, inducing both a folate receptor mediated cellular uptake and an intracellular cytotoxic actio... |
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A domino effect in antifolate drug action in Escherichia coli.
Nat. Chem. Biol. 4 , 602-8, (2008) Mass spectrometry technologies for measurement of cellular metabolism are opening new avenues to explore drug activity. Trimethoprim is an antibiotic that inhibits bacterial dihydrofolate reductase (D... |
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Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor.
Biol. Chem. 395(12) , 1461-6, (2014) An immunotoxin composed of gelonin, a basic ribosome-inactivating protein, type I of 30 kDa, isolated from the seeds of the Indian plant Gelonium multiflorum and methotrexate (MTX) has been studied as... |
7,8-Dihydropteroyl-L-glutamic acid Dihydropteroyl-L-glutamic acid |
DIHYDROFOLIC ACID |