32181-59-2

• 常用中文名：N -乙酰- D- 乳糖胺
• 常用英文名：N-Acetyl-D-lactosamine
• CAS号：32181-59-2
• 分子式：C₁₄H₂₅NO₁₁
• 分子量：383.34800
• 相关类别： 生物化工 糖类化合物 寡糖
• 发布时间：2018-08-20 19:19:46
• 更新时间：2026-07-02 11:14:12
• N-乙酰氨基乳糖(LacNAc)是一种含氮双糖,是糖蛋白和唾液酸Lewis X等多种低聚糖的重要组成部分。N-乙酰氨基乳糖可作为合成各种低聚糖的起始材料。N-乙酰氨基乳糖具有益生作用[1][2]。

名称

• 中文名: N-乙酰-D-乳糖胺
• 英文名: N-acetyllactosamine
• 中文别名: N-ACETYL-D-LACTOSAMINE N-乙酰基-D-乳糖胺; N -乙酰- D- 乳糖胺/N-Acetyl-D-lactosamine; 人层连蛋白/板层素(LN)ELISA试剂盒 YB-73125Hu; N-乙酰氨基乳糖; N-乙酰基-D-乳糖胺; N-乙酰-D-乳糖胺BSA(3原子间隔物); N-乙酰氨基乳糖(LACNAC); 人层连蛋白; N-乙酰基乳糖胺; N-乙酰-D-[UL-13C6GAL]乳糖胺; N-乙酰基-D-乳糖胺-200MM的水溶液; 猪层连蛋白/板层素(LN)ELISA试剂盒; 乙酰基乳糖胺; N-((2R,3R,4S,5R)-3,5,6-三羟基-1-氧代-4-(((2S,3R,4S,5R,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)己-2-基)乙酰胺
• 英文别名: N-ACETYL-4-O-(BETA-D-GALACTOPYRANOSYL)-D-GLUCOSAMINE; BETA-D-GALACTOPYRANOSYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE; 2-Acetamido-2-deoxy-4-O-b-d-galactopyranosyl-d-glucopyranose, Gal1-b-4GlcNAc; Galb1-4GlcNAc; 4-O-(β-D-Galactopyranosyl)-2-(acetylamino)-2-deoxy-D-glucopyranose; GAL-BETA1,4GLCNAC; D-Glucose, 2-(acetylaMino)-2-deoxy-4-O-b-D-galactopyranosyl; ACETYL LACTOSAMINE; N-ACETYL-D-LACTOSAMINE; N-Acetyl-D-lactosamine BSA (3 atom spacer); N-Acetyllactosamine; BETA-D-GAL-[1-]-D-GLCNAC; N-Acetyl-D-Lactosamine (LacNAc) ( NMR); Glucopyranose Galf1-b-4-GlcNAc; N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine; D-Glucose, 2-(acetylamino)-2-deoxy-4-O-.beta.-D-galactopyranosyl; N-Acetyl-D-Lactosamine (LacNAc); LACNAC; 2-Acetamido-2-deoxy-4-O-D-galactopyranosyl-D-glucopyranose; N-ACETYLLACTOSAMINE; 2-Acetamido-2-deoxy-D-lactose; GALF1-B-4-GLCNAC; 2-(acetylamino)-2-deoxy-4-O-hexopyranosylhexopyranose; D-Glucose, 2-(acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl; N-[(2R,4R,5S,6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-3-oxanyl]acetamide; 4-O-(β-D-Galactopyranosyl)-2-acetylamino-2-deoxy-D-glucopyranose; Gal-D-GlcNAc; β-d-gal-(1→4)-d-glcnac; N-ACETYL-4-O-(B-D-GALACTOPYRANOSYL)-D-GLUCOSAMINE; N-((2R,3R,4S,5R)-3,5,6-trihydroxy-1-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetaMide; O-BETA-D-GALACTOPYRANOSYL-BETA1,-ACETAMIDO-2-DEOXY-D-GLUCOSE; 2-Acetamido-2-deoxy-4-O-D-galactopyranosyl-D-glucopyranose, N-Acetyl-4-O-(D-galactopyranosyl)-D-glucosamine; N-Acetyllactosamine（LacNAc）; N-ACETYLLACTOSAMINE //BP; O-beta-D-Galactopyranosyl-2-deoxy-2-acetamido-D-glucose; β-D-Gal-D-GlcNAc, LN, 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine; 2-ACETAMIDO-2-DEOXY-4-O-BETA-D-GALACTOFURANOSYL-ALPHA,BETA-D-GLUCOPYRANOSE; LACNAC-GEL; N-ACETYL-LACTOSAMINE BSA; GAL1-BETA-4GLC-NAC; N-ACETYLLACTOSAMINE SYNTHETIC; LacNAc(Galb1, 4GlcNAc); N-ACETYLLACTOSAMINE-GEL; Galactopyranosyl-b-1,4-N-acetyl-D-glucosamine; LacNAc, 2-(AcetylaMino)-2-deoxy-4-O-β-D-galactopyranosyl; N-acetyl-D-[UL-13C6gal]lactosamine; N-[2,4-dihydroxy-6-(hydroxymethyl)-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-oxan-3-yl]ethanamide; GAL1-B-4GLCNAC; 2-Acetylamino-4-O-β-D-galactopyranosyl-2-deoxy-D-glucopyranose; 4)-2-deoxy-2-acetamido-D-glucose; N-Acetyllactosamine/LacNAc/Galβ1, 4GlcNAc; 4-O-β-D-Galactopyranosyl-2-(acetylamino)-2-deoxy-D-glucopyranose; 2-ACETAMIDO-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-D-GLUCOPYRANOSE; N-[(2R,3R,4S,5R)-3,5,6-trihydroxy-1-oxo-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-yl]acetamide; 2-ACETAMIDO-2-DEOXY-4-O-B-D-GALACTOFURANOSYL-A,B-D-GLUCOPYRANOSE; N-Acetyl-D-lactosamine - 200mM solution in water

物化性质

• 密度: 1.64 g/cm3
• 沸点: 805.5ºC at 760 mmHg
• 熔点: 191-192ºC
• 分子式: C₁₄H₂₅NO₁₁
• 分子量: 383.34800
• 闪点: 441ºC
• 精确质量: 383.14300
• PSA: 198.40000
• 外观性状: 白色结晶固体
• 折射率: 1.623
• 储存条件: −20°C
• 水溶解性: H2O: 10 mg/mL, clear, colorless

生物活性

• 描述: N-乙酰氨基乳糖(LacNAc)是一种含氮双糖,是糖蛋白和唾液酸Lewis X等多种低聚糖的重要组成部分。N-乙酰氨基乳糖可作为合成各种低聚糖的起始材料。N-乙酰氨基乳糖具有益生作用[1][2]。
• 相关类别:
  研究领域 >> 其他
• 靶点:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Endo T, Koizumi S, Tabata K, Kakita S, Ozaki A. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr Res. 1999 Mar 31;316(1-4):179-83.

  [2]. M.Karimi Alavijeh, et al. Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture. Biochemical Engineering Journal. Volume 154, 15 February 2020, 107459

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36/37
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3

合成路线

7512-17-6 3150-24-1 ~9% 13071-21-1 32181-59-2

文献：Tetrahedron, , vol. 68, # 9 p. 2141 - 2145

63-42-3 ~% 32181-59-2

文献：Journal of Biological Chemistry, , vol. 217, p. 79,81 Archives of Biochemistry, , vol. 54, p. 398,402

6057-48-3 ~% 32181-59-2

文献：Tohoku Journal of Experimental Medicine, , vol. 52, p. 145,146

4746-17-2 ~% 32181-59-2

文献：Chemische Berichte, , vol. 87, p. 1547,1551

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