66474-53-1

• 常用中文名：NSC 311068
• 常用英文名：NSC 311068
• CAS号：66474-53-1
• 分子式：C₁₀H₆N₄O₄S
• 分子量：278.24400
• 发布时间：2017-02-21 03:04:33
• 更新时间：2025-09-20 07:49:59
• NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.

名称

• 英文名: 2-(2,4-dinitrophenyl)sulfanylpyrimidine
• 英文别名: Jcc 216; <2,4-Dinitrophenyl>-pyrimidyl-thioaether; 1-(pyrimidin-2-ylthio)-2,4-dinitrobenzene; 2,4-Dinitropyrimidinyl-2-thiophenol; Pyrimidine,2-((2,4-dinitrophenyl)thio); 1-(2'-thiopyrimidine)-2,4-dinitrobenzene; HMS2812A16

物化性质

• 密度: 1.6g/cm3
• 沸点: 506.5ºC at 760 mmHg
• 分子式: C₁₀H₆N₄O₄S
• 分子量: 278.24400
• 闪点: 260.1ºC
• 精确质量: 278.01100
• PSA: 142.72000
• LogP: 3.49060
• 折射率: 1.7

合成路线

97-00-7 58289-71-7 ~77% 66474-53-1

文献：El-Bardan, Ali A.; Hamed, Ezzat A.; Aboul-Ela, Salah L.; Moussa, Adel M. Journal of the Indian Chemical Society, 1997 , vol. 74, # 7 p. 575 - 578

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