NSC 311068

• 常用名: NSC 311068
• 英文名: NSC 311068
• CAS号: 66474-53-1
• 分子量: 278.24400
• 密度: 1.6g/cm3
• 沸点: 506.5ºC at 760 mmHg
• 分子式: C₁₀H₆N₄O₄S
• 熔点: N/A
• 闪点: 260.1ºC

NSC 311068用途

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.

NSC 311068名称

• 英文名: 2-(2,4-dinitrophenyl)sulfanylpyrimidine

NSC 311068物理化学性质

• 密度: 1.6g/cm3
• 沸点: 506.5ºC at 760 mmHg
• 分子式: C₁₀H₆N₄O₄S
• 分子量: 278.24400
• 闪点: 260.1ºC
• 精确质量: 278.01100
• PSA: 142.72000
• LogP: 3.49060
• InChIKey: UDWLPPBHVNQRBL-UHFFFAOYSA-N
• SMILES: O=[N+]([O-])c1ccc(Sc2ncccn2)c([N+](=O)[O-])c1
• 折射率: 1.7

NSC 311068靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confir... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confirmation Assay, R21NS057026

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay 来源：24386 靶标：N/A External Id：Sarm1 TIR NADase inhibitors

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

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NSC 311068英文别名

• Jcc 216
• <2,4-Dinitrophenyl>-pyrimidyl-thioaether
• 1-(pyrimidin-2-ylthio)-2,4-dinitrobenzene
• 2,4-Dinitropyrimidinyl-2-thiophenol
• Pyrimidine,2-((2,4-dinitrophenyl)thio)
• 1-(2'-thiopyrimidine)-2,4-dinitrobenzene
• HMS2812A16