5379-94-2

• 常用中文名：3-(1-吡咯烷甲基)-1H-吲哚
• 常用英文名：1H-INDOLE, 3-(1-PYRROLIDINYLMETHYL)-
• CAS号：5379-94-2
• 分子式：C₁₃H₁₆N₂
• 分子量：200.28000
• 发布时间：2018-11-28 18:28:28
• 更新时间：2024-01-02 13:02:32

名称

• 中文名: 3-(1-吡咯烷甲基)-1H-吲哚
• 英文名: 3-(pyrrolidin-1-ylmethyl)-1H-indole
• 英文别名: 3-(1-pyrrolidinylmethyl)-1H-Indole; 3-Pyrrolidinomethyl indole; N-Skatylpyrrolidine; 1H-INDOLE,3-(1-PYRROLIDINYLMETHYL); 3-pyrrolidin-1-ylmethyl-indole

物化性质

• 密度: 1.174g/cm3
• 沸点: 350ºC at 760 mmHg
• 分子式: C₁₃H₁₆N₂
• 分子量: 200.28000
• 闪点: 165.5ºC
• 精确质量: 200.13100
• PSA: 19.03000
• LogP: 2.70160
• 折射率: 1.666

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NM1871500 CHEMICAL NAME : 1H-Indole, 3-(1-pyrrolidinylmethyl)- CAS REGISTRY NUMBER : 5379-94-2 BEILSTEIN REFERENCE NO. : 0477183 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H16-N2 MOLECULAR WEIGHT : 200.31 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 67 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 57,1814,1968

合成路线

27393-78-8 ~81% 5379-94-2

文献：Todd, Robert; Hossain, M. Mahmun Synthesis, 2009 , # 11 art. no. M07508SS, p. 1846 - 1850

123-75-1 120-72-9 75-09-2 ~63% 5379-94-2

文献：Matsumoto, Kiyoshi; Uchida, Takane; Hashimoto, Shiro; Yonezawa, Yukie; Iida, Hirokazu; et al. Heterocycles, 1993 , vol. 36, # 10 p. 2215 - 2220

75629-45-7 ~95% 5379-94-2

文献：Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

487-89-8 ~% 5379-94-2

文献：Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

上下游产品

上游产品  6
27393-78-8 123-75-1 120-72-9 75-09-2
75629-45-7 487-89-8
下游产品  0