160135-92-2

• 常用中文名：Gemopatrilat
• 常用英文名：Gemopatrilat
• CAS号：160135-92-2
• 分子式：C₁₉H₂₆N₂O₄S
• 分子量：378.48600
• 发布时间：2017-07-17 17:18:32
• 更新时间：2025-09-25 11:01:43
• A potent, orally available, dual ACE-neutral endopeptidase (vasopeptidase) inhibitor with IC50 of 12 and 63 nM, respectively.

名称

• 英文名: 2-[(6S)-2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanylpropanoyl)amino]azepan-1-yl]acetic acid
• 英文别名: Gemopatrilat (USAN/INN); hexahydro-6-[(2-mercapto-1-oxo-3-phenylpropyl)amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid; (6S)-Hexahydro-6-[[(2S)-2-mercapto-1-oxo-3-phenylpropyl]amino]-2,2-dimethyl-7-oxo-1H-azine-1-acetic acid; 2-[(6S)-2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanyl-propanoyl)amino]azan-1-yl]acetic acid; GeMopatrilat; gemopatrilat; [S-(R*,R*)]-Hexahydro-6-[2-(mercapto-1-oxo-3-phenylpropyl)amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid; Gemopatrilat (BMS-189921; Gemopatrilat [USAN]; 1H-Azine-1-acetic acid, hexahydro-6-[[(2S)-2-mercapto-1-oxo-3-phenylpropyl]amino]-2,2-dimethyl-7-oxo-, (6S); [14C]-Gemopatrilat; UNII-MU9089C77W; 2-[2,2-Dimethyl-7-oxo-6(S)-[3-phenyl-2(S)-sulfanylpropanamido]hexahydro-1H-azin-1-yl]acetic acid

物化性质

• 密度: 1.25g/cm3
• 沸点: 649.6ºC at 760 mmHg
• 分子式: C₁₉H₂₆N₂O₄S
• 分子量: 378.48600
• 闪点: 346.6ºC
• 精确质量: 378.16100
• PSA: 129.00000
• LogP: 2.66620
• 蒸汽压: 9.28E-18mmHg at 25°C
• 折射率: 1.591

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