160135-92-2
160135-92-2 structure
- Name: Gemopatrilat
- Chemical Name: 2-[(6S)-2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanylpropanoyl)amino]azepan-1-yl]acetic acid
- CAS Number: 160135-92-2
- Molecular Formula: C19H26N2O4S
- Molecular Weight: 378.48600
- Create Date: 2017-07-17 17:18:32
- Modify Date: 2024-01-03 18:27:16
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A potent, orally available, dual ACE-neutral endopeptidase (vasopeptidase) inhibitor with IC50 of 12 and 63 nM, respectively.
| Name | 2-[(6S)-2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanylpropanoyl)amino]azepan-1-yl]acetic acid |
|---|---|
| Synonyms |
Gemopatrilat (USAN/INN)
[S-(R*,R*)]-Hexahydro-6-[2-(mercapto-1-oxo-3-phenylpropyl)amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid UNII-MU9089C77W Gemopatrilat [USAN] [14C]-Gemopatrilat gemopatrilat hexahydro-6-[(2-mercapto-1-oxo-3-phenylpropyl)amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid |
| Density | 1.25g/cm3 |
|---|---|
| Boiling Point | 649.6ºC at 760 mmHg |
| Molecular Formula | C19H26N2O4S |
| Molecular Weight | 378.48600 |
| Flash Point | 346.6ºC |
| Exact Mass | 378.16100 |
| PSA | 129.00000 |
| LogP | 2.66620 |
| Vapour Pressure | 9.28E-18mmHg at 25°C |
| Index of Refraction | 1.591 |